NP_001329534.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
24,554 Da
NCBI Official Full Name
calcineurin B-like protein 1
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA CALCINEURIN B-LIKE PROTEIN; ATCBL1; calcineurin B-like protein 1; FCAALL.122; SCABP5; SOS3-LIKE CALCIUM BINDING PROTEIN 5 [Similar Products]
NCBI Protein Information
calcineurin B-like protein 1
UniProt Protein Name
Calcineurin B-like protein 1
UniProt Synonym Protein Names
SOS3-like calcium-binding protein 5
UniProt Synonym Gene Names
NCBI Summary for CBL1
Member of AtCBL (Calcineurin B-like Calcium Sensor Proteins) family. Protein level is increased upon high salt, mannitol, and cold stresses. CBL1 interacts with CIPK23 and recruits the kinase to the plasma membrane where the substrate(s) of CIPK23 may reside. CBL1 localization is regulated by protein modification including myristolation and acylation.
UniProt Comments for CBL1
Acts as a calcium sensor involved in the signaling pathway during growth and development and in response to abiotic stresses. May function as a positive regulator of salt and drought responses and as a negative regulator of cold response. Contributes to the regulation of early stress-related CBF/DREB transcription factors. CBL proteins interact with CIPK serine-threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Mediates the activation of AKT1 by CIPK proteins (CIPK6, CIPK16, and CIPK23) in response to low potassium conditions and in the context of stomatal movement. Involved in response to glucose and gibberellin during germination and seedling development and in response to cold stress. Involved in the calcium-dependent regulation by CIPK26 of reactive oxygen species production by the NADPH oxidase RBOHF.
Research Articles on CBL1
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