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anti-Rab2 antibody :: Goat Rab2 Polyclonal Antibody

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Catalog # MBS448028 (SPECIAL PROMOTIONAL PRICING for a limited time)
Unit / Price
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  0.4 mg  /  $285 +1 FREE 8GB USB
Reactivity Chart
Product Name

Rab2, Polyclonal Antibody

Popular Item
Full Product Name

Rab2 Pan Polyclonal Antibody

Product Synonym Names
Anti-Rab2; Ras-related protein Rab-2A; Ras-related protein Rab-2B antibody
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 8; NC_000008.11 (60516910..60623644). Location: 8q12.1
OMIM
179509
3D Structure
ModBase 3D Structure for P61019
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian
Specificity
Detects total levels of Rab2 protein in transfected cells with GFP-Rab2a and GFP-Rab2b by Western blot.
Form/Format
Polyclonal antibody supplied as (2 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Gene Identifier
ENSG00000104388
Immunogen
Purified recombinant peptide derived from within residues 110 aa to the C-terminus of mouse Rab2b produced in E. coli.
Antigen
Purified recombinant peptide derived from within residues 110 aa to the C-terminus of mouse Rab2b produced in E. coli.
Preparation and Storage
For continuous use, store at 2-8 deg;C for one-two days. For extended storage, store in -20 deg;C freezer. Working dilution samples should be discarded if not used within 12 hours.
Other Notes
Small volumes of anti-Rab2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Rab2 antibody
RAB2, member RAS oncogene family

RAB2 belongs to the large RAB family of low molecular weight GTPases that are involved in intracellular membrane trafficking. It has been demonstrated that Rab2 is essential for the maturation of pre-Golgi intermediates. RAB2A and RAB2B are required for protein transport from the ER to the Golgi, RAB2A is lipid-anchored to the ER-Golgi intermediate compartment membrane while RAB2B is lipid anchored to the cytoplasmic side of the cell membrane. RAB2A has been shown to interact with GOLGA2.
Applications Tested/Suitable for anti-Rab2 antibody
Western Blot (WB)
Application Notes for anti-Rab2 antibody
Western Blot: 1:250-1:2,000

Reactivity Chart of anti-Rab2 antibody
anti-Rab2 antibody Reactivity Chart image
NCBI/Uniprot data below describe general gene information for Rab2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,546 Da
NCBI Official Full Name
RAB2
NCBI Official Synonym Full Names
RAB2A, member RAS oncogene family
NCBI Official Symbol
RAB2A  [Similar Products]
NCBI Official Synonym Symbols
LHX; RAB2
  [Similar Products]
NCBI Protein Information
ras-related protein Rab-2A; small GTP binding protein RAB2A; RAB2, member RAS oncogene family
UniProt Protein Name
Ras-related protein Rab-2A
Protein Family
UniProt Gene Name
RAB2A  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
RAB2A_HUMAN
NCBI Summary for Rab2
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Comments for Rab2
Function: Required for protein transport from the endoplasmic reticulum to the Golgi complex.

Subunit structure: Interacts with PRKCI. Ref.10

Subcellular location: Endoplasmic reticulum-Golgi intermediate compartment membrane; Lipid-anchor. Melanosome. Endoplasmic reticulum membrane; Lipid-anchor

Potential. Golgi apparatus membrane; Lipid-anchor

Potential. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Ref.11

Sequence similarities: Belongs to the small GTPase superfamily. Rab family.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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