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anti-ACTR1B antibody :: Goat ACTR1B / PC3 Polyclonal Antibody

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Catalog # MBS242204
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

ACTR1B / PC3, Polyclonal Antibody

Also Known As

Goat Polyclonal to Human ACTR1B / PC3

Product Synonym Names
Anti-ACTR1B / PC3 Antibody (C-Terminus) IHC-plus; ACTR1B; Actin-related protein 1B; Beta-centractin; Centractin beta; PC3; ARP1B; CTRN2; Human ACTR1B; PC3
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
376
OMIM
605144
3D Structure
ModBase 3D Structure for P42025
Clonality
Polyclonal
Host
Goat
Species Reactivity
Bovine, Dog, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Predicted Reactivity: Bat, Hamster, Chicken, Xenopus (at least 90% immunogen sequence identity)
Specificity
Human ACTR1B. This epitope was selected to minimise the chance of cross-reactivity with ACTR1A (YEEDGARSIHRKT).
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Concentration
0.5 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic peptide C-YEEDGSRAIHRKT from the C-terminus of human ACTR1B (NP_005726.1). Percent identity by BLAST analysis: Human, Monkey, Marmoset, Mouse, Rat, Panda, Dog, Bovine, Horse, Rabbit, Pig (100%).
Immunogen Type
Synthetic peptide
Immunogen
ACTR1B / PC3 antibody was raised against synthetic peptide C-YEEDGSRAIHRKT from the C-terminus of human ACTR1B (NP_005726.1). Percent identity by BLAST analysis: Human, Monkey, Marmoset, Mouse, Rat, Panda, Dog, Bovine, Horse, Rabbit, Pig (100%); Hamster, Bat, Opossum, Turkey, Chicken, Platypus, Xenopus (92%); Gorilla, Gibbon, Elephant, Salmon, Stickleback, Zebrafish, Mosquito (85%).
Antigen Modification
C-Terminus
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Other Notes
Small volumes of anti-ACTR1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ACTR1B antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-ACTR1B antibody
ELISA (1:128000), IHC-P (3.75 ug/ml), WB (0.5 - 2 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-ACTR1B antibody
Anti-ACTR1B antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 75 ug/ml.
anti-ACTR1B antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-ACTR1B antibody
Antibody staining (1 ug/ml) of human heart lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
anti-ACTR1B antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ACTR1B. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,293 Da
NCBI Official Full Name
beta-centractin
NCBI Official Synonym Full Names
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
NCBI Official Symbol
ACTR1B  [Similar Products]
NCBI Official Synonym Symbols
PC3; ARP1B; CTRN2
  [Similar Products]
NCBI Protein Information
beta-centractin; centractin beta; actin-related protein 1B
UniProt Protein Name
Beta-centractin
UniProt Synonym Protein Names
Actin-related protein 1B; ARP1B
Protein Family
UniProt Gene Name
ACTR1B  [Similar Products]
UniProt Synonym Gene Names
CTRN2; ARP1B  [Similar Products]
UniProt Entry Name
ACTY_HUMAN
NCBI Summary for ACTR1B
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008]
UniProt Comments for ACTR1B
ACTR1B: Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. Belongs to the actin family. ARP1 subfamily.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: centrosome; dynactin complex; membrane; cytoplasm; cytosol

Molecular Function: protein binding; ATP binding

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-ACTR1B antibody
Organs/Tissues associated with anti-ACTR1B antibody
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