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anti-STX2 antibody :: Rabbit STX2 / Syntaxin 2 Polyclonal Antibody

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Catalog # MBS242500
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Immunohistochemistry (IHC)
Product Name

STX2 / Syntaxin 2, Polyclonal Antibody

Full Product Name

Rabbit Polyclonal to Rat STX2 / Syntaxin 2

Product Synonym Names
Anti-STX2 / Syntaxin 2 Antibody (aa1-19) IHC-plus; STX2; Epimorphin; EPM; EPIM; STX2B; Syntaxin-2; Stx2A; STX2C; Syntaxin 2; Rat STX2; Syntaxin 2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
132350
3D Structure
ModBase 3D Structure for P32856
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bovine, Chicken, Drosophila, Xenopus, Hamster, Human, Insect, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
Specificity
Detects an ~35 kD protein, corresponding to the apparent molecular mass of syntaxin 2 on SDSPAGE immunoblots, in samples from human, mouse, rat, bovine, canine, chicken, Drosophila, hamster, insect, monkey, pig, rabbit, sheep and Xenopus origins. The antibody specificity has been confirmed by specific peptide inhibition in immunoblotting studies.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, pH 7.2, 0.09% azide 50% glycerol.
Concentration
1 mg/ml (lot specific)
Target Species
Rat
Immunogen Description
Rat syntaxin 2 synthetic peptide, corresponding to amino acid residues 1-19, conjugated to KLH.
Immunogen Type
Synthetic peptide - KLH conjugated
Immunogen
STX2 / Syntaxin 2 antibody was raised against rat syntaxin 2 synthetic peptide, corresponding to amino acid residues 1-19, conjugated to KLH.
Antigen Modification
aa1-19
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C; Avoid freeze-thaw cycles.
Other Notes
Small volumes of anti-STX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-STX2 antibody
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Product Categories/Family for anti-STX2 antibody
Applications Tested/Suitable for anti-STX2 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-STX2 antibody
IHC-P (10 ug/ml), IP (10 ug/ml), WB (1 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-STX2 antibody
Anti-STX2 / Syntaxin 2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-STX2 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for STX2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
32,425 Da
NCBI Official Full Name
syntaxin-2 isoform 1
NCBI Official Synonym Full Names
syntaxin 2
NCBI Official Symbol
NCBI Official Synonym Symbols
EPM; EPIM; STX2A; STX2B; STX2C
  [Similar Products]
NCBI Protein Information
syntaxin-2; epimorphin
UniProt Protein Name
Syntaxin-2
UniProt Synonym Protein Names
Epimorphin
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
EPIM; STX2A; STX2B; STX2C  [Similar Products]
UniProt Entry Name
STX2_HUMAN
NCBI Summary for STX2
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for STX2
STX2: Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. Belongs to the syntaxin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Vesicle

Chromosomal Location of Human Ortholog: 12q24.33

Cellular Component: SNARE complex; extracellular space; synaptic vesicle; cell surface; intracellular membrane-bound organelle; lamellipodium; basolateral plasma membrane; integral to membrane; plasma membrane; endomembrane system; intercellular junction; lipid raft

Molecular Function: protein dimerization activity; SNAP receptor activity; SNARE binding; protein binding; calcium-dependent protein binding

Biological Process: synaptic vesicle fusion to presynaptic membrane; intracellular protein transport; organ morphogenesis; vesicle docking; response to hydroperoxide; regulation of blood coagulation; acrosome reaction; ectoderm development; cell differentiation; signal transduction; protein oligomerization; regulation of cytoskeleton organization and biogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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