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anti-DRAXIN antibody :: Rabbit C1orf187 Polyclonal Antibody

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Catalog # MBS540543
Unit / Price
  0.1 mg Affinity-Purified  /  $390 +1 FREE 8GB USB
anti-DRAXIN antibody
Product Name

C1orf187 (DRAXIN), Polyclonal Antibody

Also Known As

C1orf187 Antibody

Product Synonym Names
AGPA3119; Chromosome 1 open reading frame 187; Dorsal inhibitory axon guidance protein; Dorsal repulsive axon guidance protein; FLJ34999; MGC117222; Neucrin; UNQ3119 antibody
Matching Pairs
Antibody: C1orf187 (MBS540543)
Positive Control: C1orf187 (MBS542711)
Antibody/Peptide Pairs
C1orf187 peptide (MBS543601) is used for blocking the activity of C1orf187 antibody (MBS540543)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
349
OMIM
612682
3D Structure
ModBase 3D Structure for Q8NBI3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Rat, Chicken
Predicted: Bovine, Human, Monkey
Form/Format
Affinity Purified
Concentration
0.64 ug/ul in antibody stabilization buffer (lot specific)
Immunogen
Synthetic peptide taken within amino acid region 300-330 on C terminal region of Human Draxin protein.
Region:
NNKCFDDCMC VEGLRCYAKF HRNRRVTRRK
Molecular Function
Wnt signaling pathway
Structure
Interacts with LRP6
Subcellular Location
Secreted
Preparation and Storage
-20 degree C for long term storage
Other Notes
Small volumes of anti-DRAXIN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DRAXIN antibody
Affinity Purified Draxin Antibody
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures.
Applications Tested/Suitable for anti-DRAXIN antibody
ELISA (EIA), Immunocytochemistry (ICC), Western Blot (WB)
Application Notes for anti-DRAXIN antibody
Dot Blot: 1:20,000-1:50,000
ELISA: 1:20,000-1:50,000
Immunocytochemistry: 1:100
Western Blot: 1:500-1:1,000
NCBI/Uniprot data below describe general gene information for DRAXIN. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,650 Da[Similar Products]
NCBI Official Full Name
draxin
NCBI Official Synonym Full Names
dorsal inhibitory axon guidance protein
NCBI Official Symbol
DRAXIN  [Similar Products]
NCBI Official Synonym Symbols
UNQ3119; neucrin; AGPA3119; C1orf187
  [Similar Products]
NCBI Protein Information
draxin
UniProt Protein Name
Draxin
UniProt Synonym Protein Names
Dorsal inhibitory axon guidance protein
Protein Family
UniProt Gene Name
DRAXIN  [Similar Products]
UniProt Entry Name
DRAXI_HUMAN
UniProt Comments for DRAXIN
DRAXIN: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta- catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. Belongs to the draxin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: extracellular region

Molecular Function: protein binding

Biological Process: axon guidance; commissural neuron differentiation in the spinal cord; dorsal spinal cord development; forebrain development; negative regulation of axon extension; negative regulation of neuron apoptosis; Wnt receptor signaling pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-DRAXIN antibody
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