• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-ACKR4 antibody :: Rabbit ACKR4 / CCRL1 / CCR11 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS243853
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

ACKR4 / CCRL1 / CCR11, Polyclonal Antibody

Also Known As

Rabbit Polyclonal to Human ACKR4 / CCRL1 / CCR11

Product Synonym Names
Anti-ACKR4 / CCRL1 / CCR11 Antibody (Cytoplasmic Domain) IHC-plus; ACKR4; C-C CKR-11; CC-CKR-11; CC chemokine receptor-like 1; CCR11; CCX CKR; C-C chemokine receptor type 11; CKR-11; CCRL1; VSHK1; CCR-11; CCX-CKR; PPR1; Human ACKR4; CCRL1; CCR11
Product Synonym Gene Name
CCRL1; CCR11[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
350
OMIM
606065
3D Structure
ModBase 3D Structure for Q9NPB9
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bat, Gibbon, Dog, Gorilla, Horse, Human, Mouse, Pig, Rabbit, Rat
Predicted Reactivity: Monkey, Bovine, Hamster (at least 90% immunogen sequence identity)
Specificity
Human CCRL1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CCR6 (63%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human CCRL1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Dog, Bat, Elephant, Panda, Horse, Rabbit, Pig (100%); Marmoset, Bovine.
Immunogen Type
Synthetic peptide
Immunogen
ACKR4 / CCRL1 / CCR11 antibody was raised against synthetic 16 amino acid peptide from 1st cytoplasmic domain of human CCRL1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Dog, Bat, Elephant, Panda, Horse, Rabbit, Pig (100%); Marmoset, Bovine, Hamster, Opossum (94%); Turkey, Chicken, Xenopus (81%).
Antigen Modification
Cytoplasmic Domain
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Other Notes
Small volumes of anti-ACKR4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACKR4 antibody
CCRL1, a Chemokine Receptor, responds to monocyte chemoattractant proteins (MCP) (Schweickart et al., 2000).
Applications Tested/Suitable for anti-ACKR4 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-ACKR4 antibody
IHC-P (24 ug/ml)

Immunohistochemistry (IHC) of anti-ACKR4 antibody
Anti-ACKR4 / CCRL1 / CCR11 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-ACKR4 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ACKR4 antibody
Anti-ACKR4 / CCRL1 / CCR11 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-ACKR4 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ACKR4 antibody
Anti-CCRL1 antibody IHC of human heart, cardiac myocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-ACKR4 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ACKR4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,914 Da
NCBI Official Full Name
atypical chemokine receptor 4
NCBI Official Synonym Full Names
atypical chemokine receptor 4
NCBI Official Symbol
ACKR4  [Similar Products]
NCBI Official Synonym Symbols
PPR1; CCBP2; CCR10; CCR11; CCRL1; VSHK1; CCR-11; CKR-11; CCX CKR; CCX-CKR; CC-CKR-11
  [Similar Products]
NCBI Protein Information
atypical chemokine receptor 4; C-C CKR-11; CC chemokine receptor-like 1; C-C chemokine receptor type 11; chemocentryx chemokine receptor; chemokine (C-C motif) receptor-like 1; chemokine, cc motif, receptor-like protein 1; orphan seven-transmembrane receptor, chemokine related
UniProt Protein Name
Atypical chemokine receptor 4
UniProt Synonym Protein Names
C-C chemokine receptor type 11; C-C CKR-11; CC-CKR-11; CCR-11; CC chemokine receptor-like 1; CCRL1; CCX CKR
UniProt Gene Name
ACKR4  [Similar Products]
UniProt Synonym Gene Names
CCBP2; CCR11; CCRL1; VSHK1; C-C CKR-11; CC-CKR-11; CCR-11; CCRL1  [Similar Products]
UniProt Entry Name
ACKR4_HUMAN
NCBI Summary for ACKR4
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2013]
UniProt Comments for ACKR4
CCRL1: Receptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3q22

Cellular Component: recycling endosome; integral to plasma membrane; early endosome; plasma membrane

Molecular Function: protein binding; chemokine receptor activity; chemokine binding; scavenger receptor activity

Biological Process: receptor-mediated endocytosis; G-protein coupled receptor protein signaling pathway; immune response; chemotaxis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000