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anti-NR2F2 antibody :: NR2F2 Polyclonal Antibody

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Catalog # MBS8216179
Unit / Price
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

NR2F2, Polyclonal Antibody

Popular Item
Also Known As

Anti-NR2F2 Antibody

Product Synonym Names
ARP1; TFCOUP2; COUP transcription factor 2; COUP-TF2; Apolipoprotein A-I regulatory protein 1; ARP-1; COUP transcription factor II; COUP-TF II; Nuclear receptor subfamily 2 group F member 2
Antibody/Peptide Pairs
NR2F2 peptide (MBS8212016) is used for blocking the activity of NR2F2 antibody (MBS8216179)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
261
OMIM
107773
3D Structure
ModBase 3D Structure for P24468
Clonality
Polyclonal
Species Reactivity
Human, Mouse, Rat, Bovine, Dog, Porcine
Specificity
Recognizes endogenous levels of NR2F2 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Source
Rabbit
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NR2F2. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-NR2F2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NR2F2 antibody
Rabbit polyclonal antibody to NR2F2
Applications Tested/Suitable for anti-NR2F2 antibody
Western Blot (WB),Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-NR2F2 antibody
WB (1/500 - 1/1000), IHC (1/100 - 1/200), IF/ICC (1/100 - 1/500)

Western Blot (WB) of anti-NR2F2 antibody
Western blot analysis of NR2F2 expression in HepG2 (A), HeLa (B) whole cell lysates.
anti-NR2F2 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-NR2F2 antibody
Immunohistochemical analysis of NR2F2 staining in human kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
anti-NR2F2 antibody Immunohistochemistry (IHC) (IHC) image
Immunofluorescence (IF) of anti-NR2F2 antibody
Immunofluorescent analysis of NR2F2 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 degree C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
anti-NR2F2 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for NR2F2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,163 Da
NCBI Official Full Name
COUP transcription factor 2 isoform b
NCBI Official Synonym Full Names
nuclear receptor subfamily 2, group F, member 2
NCBI Official Symbol
NR2F2  [Similar Products]
NCBI Official Synonym Symbols
ARP1; CHTD4; NF-E3; NR2F1; SVP40; COUPTFB; TFCOUP2; COUPTFII
  [Similar Products]
NCBI Protein Information
COUP transcription factor 2
UniProt Protein Name
COUP transcription factor 2
UniProt Synonym Protein Names
Apolipoprotein A-I regulatory protein 1; ARP-1; COUP transcription factor II; COUP-TF II; Nuclear receptor subfamily 2 group F member 2
Protein Family
UniProt Gene Name
NR2F2  [Similar Products]
UniProt Synonym Gene Names
ARP1; TFCOUP2; COUP-TF2; ARP-1; COUP-TF II  [Similar Products]
UniProt Entry Name
COT2_HUMAN
NCBI Summary for NR2F2
This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
UniProt Comments for NR2F2
NR2F2: Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. Interacts with SQSTM1. Binds DNA as a dimer; homodimer or heterodimer with NR2F6. Interacts with NCOA1, NCOA2, NCOA3 and PPARGC1A. Interacts with ZFPM2. Ubiquitous. Belongs to the nuclear hormone receptor family. NR2 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Motility/polarity/chemotaxis; Nuclear receptor

Chromosomal Location of Human Ortholog: 15q26

Cellular Component: nucleus

Molecular Function: ligand-dependent nuclear receptor activity; protein binding; protein homodimerization activity; retinoic acid binding; zinc ion binding; sequence-specific DNA binding; steroid hormone receptor activity; transcription corepressor activity; transcription factor activity

Biological Process: limb development; skeletal muscle development; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; neuron migration; negative regulation of cyclin-dependent protein kinase activity; negative regulation of transcription from RNA polymerase II promoter; signal transduction; response to estradiol stimulus; regulation of transcription from RNA polymerase II promoter; anterior/posterior pattern formation; fertilization; negative regulation of endothelial cell proliferation; forebrain development; blood vessel morphogenesis; steroid hormone mediated signaling; lipid metabolic process; negative regulation of transcription, DNA-dependent; radial pattern formation; maternal placenta development

Disease: Congenital Heart Defects, Multiple Types, 4
Research Articles on NR2F2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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