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anti-MFI2 antibody :: Rabbit MFI2 / p97 / Melanotransferrin Polyclonal Antibody

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Catalog # MBS241517
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

MFI2 / p97 / Melanotransferrin, Polyclonal Antibody

Full Product Name

Rabbit Polyclonal to Human MFI2 / p97 / Melanotransferrin

Product Synonym Names
Anti-MFI2 / p97 / Melanotransferrin Antibody (N-Terminus) IHC-plus; MFI2; Antigen p97; CD228; CD228 antigen; MAP97; Melanotransferrin; p97; Human MFI2; p97; Melanotransferrin
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
155750
3D Structure
ModBase 3D Structure for P08582
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bat, Gibbon, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Rat
Predicted Reactivity: Bovine, Pig, Rabbit (at least 90% immunogen sequence identity)
Specificity
Human MFI2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic 15 amino acid peptide from N-terminus of human MFI2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bat, Hamster, Elephant, Panda, Horse (100%); Bovine, Rabbit, Pig (93%).
Immunogen Type
Synthetic peptide
Immunogen
MFI2 / p97 / Melanotransferrin antibody was raised against synthetic 15 amino acid peptide from N-terminus of human MFI2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bat, Hamster, Elephant, Panda, Horse (100%); Bovine, Rabbit, Pig (93%); Chicken, Platypus (87%); Dog, Turkey, Medaka, Zebrafish (80%).
Antigen Modification
N-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Other Notes
Small volumes of anti-MFI2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-MFI2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-MFI2 antibody
IHC-P (15 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-MFI2 antibody
Anti-MFI2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-MFI2 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-MFI2 antibody
Anti-MFI2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-MFI2 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for MFI2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
32,723 Da
NCBI Official Full Name
melanotransferrin isoform 1
NCBI Official Synonym Full Names
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
NCBI Official Symbol
NCBI Official Synonym Symbols
MTF1; CD228; MAP97
  [Similar Products]
NCBI Protein Information
melanotransferrin; membrane-bound transferrin-like protein; melanoma-associated antigen p97, isoform 2
UniProt Protein Name
Melanotransferrin
UniProt Synonym Protein Names
Melanoma-associated antigen p97; CD_antigen: CD228
UniProt Gene Name
UniProt Synonym Gene Names
MAP97  [Similar Products]
UniProt Entry Name
TRFM_HUMAN
NCBI Summary for MFI2
The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. [provided by RefSeq, Jul 2008]
UniProt Comments for MFI2
MFI2: Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc. Belongs to the transferrin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 3q28-q29

Cellular Component: cell surface; anchored to plasma membrane; integral to plasma membrane

Molecular Function: protein binding; ferric iron binding; iron ion binding

Biological Process: cellular iron ion homeostasis; regulation of cell growth; regulation of cell proliferation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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