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anti-S100A9 antibody :: Goat S100A9 / MRP14 Polyclonal Antibody

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Catalog # MBS242631
Unit / Price
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  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

S100A9 / MRP14, Polyclonal Antibody

Full Product Name

Goat Polyclonal to Human S100A9 / MRP14

Product Synonym Names
Anti-S100A9 / MRP14 Antibody (Internal) IHC-plus; S100A9; 60B8AG; Calgranulin B; CFAG; CAGB; Calgranulin-B; Calprotectin L1H subunit; CGLB; L1Ag; MRP14; NIF; p14; Protein S100-A9; LIAG; MAC387; MRP-14; Human S100A9; MRP14
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
123886
3D Structure
ModBase 3D Structure for P06702
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gibbon, Gorilla, Human
Predicted Reactivity: Monkey, Bovine, Hamster, Horse, Pig, Rabbit (at least 90% immunogen sequence identity)
Specificity
Human S100A9.
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Concentration
0.5 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic peptide C-DTNADKQLSFEEF from an internal region of human S100A9 (NP_002956.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Hamster, Bovine, Rabbit, Horse, Pig (92%); Panda (85%).
Immunogen Type
Synthetic peptide
Immunogen
S100A9 / MRP14 antibody was raised against synthetic peptide C-DTNADKQLSFEEF from an internal region of human S100A9 (NP_002956.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Hamster, Bovine, Rabbit, Horse, Pig (92%); Panda (85%).
Antigen Modification
Internal
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Other Notes
Small volumes of anti-S100A9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-S100A9 antibody
Also known as S100 calcium-binding protein A9 and migration inhibitory factor-related protein 14.
Applications Tested/Suitable for anti-S100A9 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-S100A9 antibody
ELISA (1:8000, 0.3 - 1 ug/ml), IHC-P (2.5 ug/ml), WB (0.3 - 1 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-S100A9 antibody
Anti-S100A9 / MRP14 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
anti-S100A9 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-S100A9 antibody
Anti-S100A9 / MRP14 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
anti-S100A9 antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-S100A9 antibody
Antibody (0.5 ug/ml) staining of Human Peripheral Mononucleocytes lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-S100A9 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for S100A9. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
13,242 Da
NCBI Official Full Name
protein S100-A9
NCBI Official Synonym Full Names
S100 calcium binding protein A9
NCBI Official Symbol
S100A9  [Similar Products]
NCBI Official Synonym Symbols
MIF; NIF; P14; CAGB; CFAG; CGLB; L1AG; LIAG; MRP14; 60B8AG; MAC387
  [Similar Products]
NCBI Protein Information
protein S100-A9; MRP-14; calgranulin B; calgranulin-B; calprotectin L1H subunit; leukocyte L1 complex heavy chain; migration inhibitory factor-related protein 14; S100 calcium-binding protein A9 (calgranulin B)
UniProt Protein Name
Protein S100-A9
UniProt Synonym Protein Names
Calgranulin-B; Calprotectin L1H subunit; Leukocyte L1 complex heavy chain; Migration inhibitory factor-related protein 14; MRP-14; p14; S100 calcium-binding protein A9
Protein Family
UniProt Gene Name
S100A9  [Similar Products]
UniProt Synonym Gene Names
CAGB; CFAG; MRP14; MRP-14; p14  [Similar Products]
UniProt Entry Name
S10A9_HUMAN
NCBI Summary for S100A9
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. This antimicrobial protein exhibits antifungal and antibacterial activity. [provided by RefSeq, Nov 2014]
UniProt Comments for S100A9
S100A9: a calcium-binding regulatory protein of the S-100 family expressed by macrophages in acutely inflammated tissues and in chronic inflammations. May be an inhibitor of protein kinases. Also expressed in epithelial cells constitutively or induced during dermatoses. May interact with components of the intermediate filaments in monocytes and epithelial cells. Interacts with CEACAM3 in a calcium-dependent manner.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: extracellular space; cytoskeleton; extracellular region; plasma membrane; nucleus; cytosol

Molecular Function: arachidonic acid binding; antioxidant activity; RAGE receptor binding; protein binding; signal transducer activity; zinc ion binding; microtubule binding; calcium ion binding

Biological Process: caspase activation; neutrophil chemotaxis; chemokine production; chronic inflammatory response; cytokine production; response to lipopolysaccharide; positive regulation of peptide secretion; signal transduction; positive regulation of cell growth; leukocyte migration during inflammatory response; activation of NF-kappaB transcription factor; sequestering of zinc ion; response to ethanol; cell-cell signaling; response to zinc ion; defense response to bacterium; actin cytoskeleton reorganization; autophagy; innate immune response; regulation of integrin biosynthetic process; inflammatory response; defense response to fungus; regulation of cytoskeleton organization and biogenesis; positive regulation of inflammatory response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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