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VAMP7 antibody pair

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Catalog # MBS7041798
Unit / Price
  1 Pair (Sufficient for 5x96 well plates)  /  $735 +1 FREE 8GB USB
VAMP7 antibody pair
Product Name

VAMP7, Antibody Pair

Also Known As

VAMP7 Antibody Pair

Product Synonym Names
Vesicle-associated membrane protein 7; Synaptobrevin-like protein 1; Tetanus-insensitive VAMP
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
179
OMIM
300053
Clonality
Polyclonal
Isotype
Capture: IgG
Detection: IgG
Host
Capture: Rabbit
Detection: Rabbit
Species Reactivity
Human, Bovine, Horse, Pig, Goat
Form/Format
Liquid
Concentration
The concentrations and volumes of the antibodies may vary and be lot specific. Details will be on the vial labels. (lot specific)
Immunogen Species
Human
Conjugation
Capture: Non-conjugated; Detection: Biotin conjugated
Recommended Standard
OVCAR-4 cell; PC-3 cell
(Standards are recommendations only. Compatibility of the standards in the user developed application needs to be established and confirmed by the researcher.
Storage Buffer
Capture: 50% Glycerol, 0.01M PBS, PH 7.4
Detection: 50% Glycerol, 0.01M PBS, PH 7.4
Other Note
Immunogen information is company proprietary information. Antibodies are sold as a pair and not available separately.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze/thaw cycles. When stored properly, products should be stable for at least 5 months.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of VAMP7 antibody pair vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for VAMP7 antibody pair
Sandwich ELISA (EIA)
Application Notes for VAMP7 antibody pair
We recommend using the capture antibody at a concentration of 0.5ug/ml and the detection antibody at a concentration of 0.2ug/ml.
NCBI/Uniprot data below describe general gene information for VAMP7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20,121 Da
NCBI Official Full Name
vesicle-associated membrane protein 7 isoform 2
NCBI Official Synonym Full Names
vesicle associated membrane protein 7
NCBI Official Symbol
VAMP7  [Similar Products]
NCBI Official Synonym Symbols
SYBL1; TIVAMP; VAMP-7; TI-VAMP
  [Similar Products]
NCBI Protein Information
vesicle-associated membrane protein 7
UniProt Protein Name
Vesicle-associated membrane protein 7
UniProt Synonym Protein Names
Synaptobrevin-like protein 1; Tetanus-insensitive VAMP; Ti-VAMP
UniProt Gene Name
VAMP7  [Similar Products]
UniProt Synonym Gene Names
SYBL1; VAMP-7; Ti-VAMP  [Similar Products]
UniProt Entry Name
VAMP7_HUMAN
NCBI Summary for VAMP7
This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
UniProt Comments for VAMP7
VAMP7: Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation. Belongs to the synaptobrevin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq28 and Yq12

Cellular Component: apical part of cell; cell junction; cell surface; cytoplasm; endoplasmic reticulum membrane; integral to membrane; intracellular membrane-bound organelle; lamellipodium; late endosome membrane; lysosomal membrane; membrane; neuron projection; perinuclear region of cytoplasm; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane; pseudopodium; secretory granule; secretory granule membrane; SNARE complex; synapse; trans-Golgi network

Molecular Function: protein binding; SNAP receptor activity; SNARE binding; syntaxin binding

Biological Process: calcium ion-dependent exocytosis; endocytosis; endosome to lysosome transport; eosinophil degranulation; ER to Golgi vesicle-mediated transport; Golgi to plasma membrane protein transport; natural killer cell degranulation; neutrophil degranulation; phagocytosis, engulfment; positive regulation of dendrite morphogenesis; post-Golgi vesicle-mediated transport; triacylglycerol transport; vesicle fusion; vesicle fusion with Golgi apparatus; vesicle transport along microtubule; vesicle-mediated transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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