• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-MFAP5 antibody :: Rabbit MFAP5 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS9204084
Unit / Price
Scan QR to view Datasheet
  0.08 mL  /  $165 +1 FREE 8GB USB
  0.4 mL  /  $370 +1 FREE 8GB USB
Product Name

MFAP5, Polyclonal Antibody

Popular Item
Full Product Name

MFAP5 Antibody (C-term)

Product Synonym Names
Microfibrillar-associated protein 5; MFAP-5; MP25; Microfibril-associated glycoprotein 2; MAGP-2; MFAP5; MAGP2
Antibody/Peptide Pairs
MFAP5 peptide (MBS9226785) is used for blocking the activity of MFAP5 antibody (MBS9204084)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
133-160
OMIM
601103
3D Structure
ModBase 3D Structure for Q13361
Clonality
Polyclonal
Isotype
Rabbit Ig
Clone Number
RB18639
Host
Rabbit
Species Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Specificity
This MFAP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from the C-terminal region of human MFAP5.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity). Component of the elastin-associated microfibrils (PubMed:8557636).
Calculated MW
19612
Cellular Location
Secreted, extracellular space, extracellular matrix
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-MFAP5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MFAP5 antibody
MFAP5 is a 25-kD microfibril-associated glycoprotein which is rich in serine and threonine residues. The protein lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are characteristics of a related 31-kDa microfibril-associated glycoprotein (MFAP2). The close similarity between these two proteins is confined to a central region of 60 aa where precise alignment of 7 cysteine residues occurs. The structural differences suggest that this protein has some functions that are distinct from those of MFAP2.
Product Categories/Family for anti-MFAP5 antibody
Applications Tested/Suitable for anti-MFAP5 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P), Flow Cytometry (FC/FACS)
Application Notes for anti-MFAP5 antibody
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50

Western Blot (WB) of anti-MFAP5 antibody
Western blot analysis of MFAP5 antibody (C-term) in K562 cell line lysates (35ug/lane). MFAP5 (arrow) was detected using the purified Pab.
anti-MFAP5 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-MFAP5 antibody
Formalin-fixed and paraffin-embedded human Skeletal muscle reacted with MFAP5 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
anti-MFAP5 antibody Immunohistochemistry (IHC) (IHC) image
Flow Cytometry (FC/FACS) of anti-MFAP5 antibody
MFAP5 Antibody (C-term) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
anti-MFAP5 antibody Flow Cytometry (FC/FACS) (FC/FACS) image
Western Blot (WB) of anti-MFAP5 antibody
Western blot analysis of MFAP5 (arrow) using rabbit polyclonal MFAP5 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MFAP5 gene.
anti-MFAP5 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for MFAP5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
microfibrillar-associated protein 5 isoform a
NCBI Official Synonym Full Names
microfibrillar associated protein 5
NCBI Official Symbol
MFAP5  [Similar Products]
NCBI Official Synonym Symbols
AAT9; MP25; MAGP2; MAGP-2; MFAP-5
  [Similar Products]
NCBI Protein Information
microfibrillar-associated protein 5
UniProt Protein Name
Microfibrillar-associated protein 5
UniProt Synonym Protein Names
MP25; Microfibril-associated glycoprotein 2; MAGP-2
UniProt Gene Name
MFAP5  [Similar Products]
UniProt Synonym Gene Names
MAGP2; MFAP-5; MAGP-2  [Similar Products]
UniProt Entry Name
MFAP5_HUMAN
NCBI Summary for MFAP5
This gene encodes a 25-kD microfibril-associated glycoprotein which is a component of microfibrils of the extracellular matrix. The encoded protein promotes attachment of cells to microfibrils via alpha-V-beta-3 integrin. Deficiency of this gene in mice results in neutropenia. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
UniProt Comments for MFAP5
MFAP5: Component of the elastin-associated microfibrils. Belongs to the MFAP family.

Protein type: Secreted, signal peptide; Secreted; Extracellular matrix

Chromosomal Location of Human Ortholog: 12p13.1-p12.3

Cellular Component: microfibril; extracellular region

Molecular Function: extracellular matrix structural constituent

Biological Process: extracellular matrix organization and biogenesis; fibril organization and biogenesis

Disease: Aortic Aneurysm, Familial Thoracic 9
Product References and Citations for anti-MFAP5 antibody
Albig,A.R., Becenti,D.J. Microvasc. Res. 76 (1), 7-14 (2008)
Miyamoto,A., Lau,R. J. Biol. Chem. 281 (15), 10089-10097 (2006)
Penner,A.S., Rock,M.J. J. Biol. Chem. 277 (38), 35044-35049 (2002)
Hatzinikolas,G. J. Biol. Chem. 273 (45), 29309-29314 (1998)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-MFAP5 antibody
Pathways associated with anti-MFAP5 antibody
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000