• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-ABCD3 antibody :: Rabbit ABCD3 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS820545
Unit / Price
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
anti-ABCD3 antibody
Product Name

ABCD3, Polyclonal Antibody

Also Known As

Anti-ABCD3 Antibody

Product Synonym Names
PMP70; PXMP1; ATP-binding cassette sub-family D member 3; 70 kDa peroxisomal membrane protein; PMP70
Antibody/Peptide Pairs
ABCD3 peptide (MBS823410) is used for blocking the activity of ABCD3 antibody (MBS820545)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
236
OMIM
170995
3D Structure
ModBase 3D Structure for P28288
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine
Specificity
Recognizes endogenous levels of ABCD3 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ABCD3. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-ABCD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABCD3 antibody
Rabbit polyclonal antibody to ABCD3
Applications Tested/Suitable for anti-ABCD3 antibody
Western Blot (WB)
Application Notes for anti-ABCD3 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-ABCD3 antibody
anti-ABCD3 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ABCD3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,121 Da
NCBI Official Full Name
ATP-binding cassette sub-family D member 3 isoform b
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family D (ALD), member 3
NCBI Official Symbol
ABCD3  [Similar Products]
NCBI Official Synonym Symbols
ZWS2; ABC43; PMP70; PXMP1
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family D member 3; 70 kDa peroxisomal membrane protein; Peroxisomal membrane protein-1 (70kD); peroxisomal membrane protein 1 (70kD, Zellweger syndrome); dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1))
UniProt Protein Name
ATP-binding cassette sub-family D member 3
UniProt Synonym Protein Names
70 kDa peroxisomal membrane protein; PMP70
Protein Family
UniProt Gene Name
ABCD3  [Similar Products]
UniProt Synonym Gene Names
PMP70; PXMP1; PMP70  [Similar Products]
UniProt Entry Name
ABCD3_HUMAN
NCBI Summary for ABCD3
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCD3
ABCD3: a member of the superfamily of ATP-binding cassette (ABC) transporters. Likely plays an important role in peroxisome biogenesis. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. Defects in ABCD3 may be the cause of Zellweger syndrome-2 (ZWS-2), an autosomal recessive disorder due to defective import mechanisms for peroxisomal matrix enzymes.

Protein type: Mitochondrial; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ABC family

Chromosomal Location of Human Ortholog: 1p21.3

Cellular Component: peroxisomal membrane; peroxisomal matrix; intracellular membrane-bound organelle; membrane; mitochondrial inner membrane; integral to membrane; peroxisome; cytosol

Molecular Function: protein binding; protein homodimerization activity; ATPase activity, coupled to transmembrane movement of substances; ATPase activity; ATP binding

Biological Process: fatty acid beta-oxidation; very-long-chain fatty acid catabolic process; peroxisome organization and biogenesis; transmembrane transport

Disease: Bile Acid Synthesis Defect, Congenital, 5
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000