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anti-GORASP2 antibody :: GRASP55 Polyclonal Antibody

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Catalog # MBS821004
Unit / Price
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

GRASP55 (GORASP2), Polyclonal Antibody

Popular Item
Also Known As

Anti-GRASP55 Antibody

Product Synonym Names
GOLPH6; Golgi reassembly-stacking protein 2; GRS2; Golgi phosphoprotein 6; GOLPH6; Golgi reassembly-stacking protein of 55 kDa; GRASP55; p59
Antibody/Peptide Pairs
GRASP55 peptide (MBS823863) is used for blocking the activity of GRASP55 antibody (MBS821004)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
384
OMIM
608693
3D Structure
ModBase 3D Structure for Q9H8Y8
Clonality
Polyclonal
Species Reactivity
Human, Mouse, Rat, Bovine
Specificity
Recognizes endogenous levels of GRASP55 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Source
Rabbit
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GRASP55. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-GORASP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GORASP2 antibody
Rabbit polyclonal antibody to GRASP55
Applications Tested/Suitable for anti-GORASP2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Application Notes for anti-GORASP2 antibody
WB (1/500 - 1/1000); IHC (1/100 - 1/200); IP (1/10 - 1/100)

Western Blot (WB) of anti-GORASP2 antibody
Western blot analysis of GRASP55 expression in HepG2 (A), Raji (B), LOVO (C) whole cell lysates.
anti-GORASP2 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-GORASP2 antibody
Immunohistochemical analysis of GRASP55 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
anti-GORASP2 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for GORASP2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,674 Da
NCBI Official Full Name
Golgi reassembly-stacking protein 2 isoform 2
NCBI Official Synonym Full Names
golgi reassembly stacking protein 2, 55kDa
NCBI Official Symbol
GORASP2  [Similar Products]
NCBI Official Synonym Symbols
p59; GRS2; GOLPH6; GRASP55
  [Similar Products]
NCBI Protein Information
Golgi reassembly-stacking protein 2; golgi phosphoprotein 6
UniProt Protein Name
Golgi reassembly-stacking protein 2
UniProt Synonym Protein Names
Golgi phosphoprotein 6; GOLPH6; Golgi reassembly-stacking protein of 55 kDa; GRASP55; p59
UniProt Gene Name
GORASP2  [Similar Products]
UniProt Synonym Gene Names
GOLPH6; GRS2; GOLPH6; GRASP55  [Similar Products]
UniProt Entry Name
GORS2_HUMAN
NCBI Summary for GORASP2
This gene encodes a member of the Golgi reassembly stacking protein family. These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation, as well as Golgi fragmentation during apoptosis or mitosis. The encoded protein also plays a role in the intracellular transport of transforming growth factor alpha and may function as a molecular chaperone. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
UniProt Comments for GORASP2
GRASP55: a golgi reassembly-stacking protein (GRASP) protein involved in the stacking of Golgi cisternae. May be involved in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as the TGF-alpha receptor. Oligomerization of its N-terminal GRASP domain regulates the formation of Golgi stacks, a process that is regulated by phosphorylation within the C-terminal Ser/Pro-rich domain. Forms a RAB2 effector complex with BLZF1 in the medial Golgi. Interacts with members of the p24 cargo receptors. Interacts with CNIH and the cytoplasmic domain of the TGF-alpha receptor, prior its transit in the trans-Golgi. Two alternatively spliced isoforms have been described.

Protein type: Vesicle; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q31.1

Cellular Component: Golgi membrane; Golgi apparatus; membrane

Molecular Function: protein binding

Biological Process: organelle organization and biogenesis; mitotic cell cycle
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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