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anti-RAB35 antibody :: Rabbit RAB35 Polyclonal Antibody

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Catalog # MBS820169
Unit / Price
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
anti-RAB35 antibody
Product Name

RAB35, Polyclonal Antibody

Popular Item
Full Product Name

Anti-RAB35 Antibody

Product Synonym Names
RAB1C; RAY; Ras-related protein Rab-35; GTP-binding protein RAY; Ras-related protein Rab-1C
Antibody/Peptide Pairs
RAB35 peptide (MBS823899) is used for blocking the activity of RAB35 antibody (MBS820169)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
604199
3D Structure
ModBase 3D Structure for Q15286
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine
Specificity
Recognizes endogenous levels of RAB35 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human RAB35. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-RAB35 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-RAB35 antibody
Rabbit polyclonal antibody to RAB35
Applications Tested/Suitable for anti-RAB35 antibody
Western Blot (WB)
Application Notes for anti-RAB35 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-RAB35 antibody
anti-RAB35 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for RAB35. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,058 Da
NCBI Official Full Name
ras-related protein Rab-35 isoform 2
NCBI Official Synonym Full Names
RAB35, member RAS oncogene family
NCBI Official Symbol
RAB35  [Similar Products]
NCBI Official Synonym Symbols
RAY; H-ray; RAB1C
  [Similar Products]
NCBI Protein Information
ras-related protein Rab-35; GTP-binding protein RAY; ras-related protein rab-1c (GTP-binding protein ray)
UniProt Protein Name
Ras-related protein Rab-35
UniProt Synonym Protein Names
GTP-binding protein RAY; Ras-related protein Rab-1C
Protein Family
UniProt Gene Name
RAB35  [Similar Products]
UniProt Synonym Gene Names
RAB1C; RAY  [Similar Products]
UniProt Entry Name
RAB35_HUMAN
UniProt Comments for RAB35
RAB35: In the process of endocytosis, essential rate-limiting regulator of a fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. Interacts with DENND1A and DENND1B in a nucleotide- dependent manner. The low binding to DENND1C is nucleotide- independent. All 3 DENND1 act as GEFs for RAB35 and thus activate the protein. Belongs to the small GTPase superfamily. Rab family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: Golgi membrane; endoplasmic reticulum membrane; intercellular bridge; mitochondrion; cell projection membrane; plasma membrane; melanosome; coated pit; endosome membrane; clathrin-coated endocytic vesicle

Molecular Function: GTPase activity; phosphatidylinositol-4,5-bisphosphate binding; protein binding; GDP binding; GTP binding

Biological Process: intracellular protein transport; antigen processing and presentation; protein localization; ER to Golgi vesicle-mediated transport; metabolic process; cytokinesis; plasma membrane to endosome transport; Rab protein signal transduction; endosome transport; endocytic recycling; neurite development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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