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anti-Csp antibody :: Rabbit Cysteine String Protein Polyclonal Antibody

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Catalog # MBS614840
Unit / Price
  0.1 mg  /  $540 +1 FREE 8GB USB
anti-Csp antibody
Product Name

Cysteine String Protein (Csp), Polyclonal Antibody

Also Known As

Cysteine String Protein (CSP)

Product Synonym Names
Anti -Cysteine String Protein (CSP)
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 3L; NT_037436.3 (22260361..22266846). Location: 79D3-79D3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Bovine, Mouse, Rat, Xenopus
Specificity
This immunoaffinity purified antibody detects a 34kD protein, corresponding to the apparent molecular mass of CSP on SDS-PAGE immunoblots, in samples from mouse, rat, bovine and Xenopus. A 70kD band is also observed, which may represent a CSP
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in borate buffered saline, pH 8.2 25mM sodium borate, 100mM boric acid, 75mM sodium chloride, 5mM EDTA (disodium salt).
Immunogen
A 17 residue synthetic peptide (C)TQLTADSHPSYHTDGFN based on the rat cysteine string protein (residues 182-198) with the cysteine (C) residue added and the peptide coupled to KLH.
Preparation and Storage
-20 degree C
Other Notes
Small volumes of anti-Csp antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Csp antibody
Cysteine string protein (CSP) is a 34kD rat brain protein localized to the cytoplasmic surface of the synaptic vesicle, possibly via palmitoylation (1,2). CSP homologs are localized to the nervous system of Drosophila and to cholinergic vesicles of Torpedo (3,4). The amino terminus of CSP contains the J domain, a consensus sequence found on a DnaJ like protein which is a member of the heat-shock protein family (5). Since heat shock proteins serve as chaperones that participate in protein folding and protein complex formation, CSP is believed to perform similar functions in the assembly of synaptic vesicle proteins which are essential to membrane trafficking. Evidence for a role of CSP in presynaptic neurotransmitter release has come from genetic and physiological study in which the Drosophila CSP null mutant fails to elicit synaptic potential upon high frequency stimulation (6). CSP null mutants have a lethal phenotype and for the small percentage of mutant flies that survive, they become paralyzed and die at elevated temperature (7).
Product Categories/Family for anti-Csp antibody
Applications Tested/Suitable for anti-Csp antibody
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for Csp. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
cysteine string protein, isoform C
NCBI Official Synonym Full Names
Cysteine string protein
NCBI Official Symbol
NCBI Official Synonym Symbols
ab49; anon-WO02059370.50; CG6395; csp; CSP; csp29; csp32; CSP32; Cys; D-CSP; D.M.CSP; Dcsp; DCSP-1; DmelCG6395; l(3)03988; MAB ab49
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NCBI Protein Information
CG6395 gene product from transcript CG6395-RB; cysteine string protein, isoform B; CG6395-PB; Csp-PB; cysteine string protein 3; cysteine-string protein; cystein string protein; cysteine string protein, isoform A; CG6395-PA; Csp-PA; cysteine string protein, isoform C; CG6395-PC; Csp-PC
Protein Family
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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