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anti-ACTA2 antibody :: Rabbit Alpha smooth muscle Actin Polyclonal Antibody

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Catalog # MBS9200862
Unit / Price
  0.1 mL  /  $340 +1 FREE 8GB USB
Western Blot (WB)
Product Name

Alpha smooth muscle Actin (ACTA2), Polyclonal Antibody

Popular Item
Also Known As

Alpha smooth muscle Actin Antibody

Product Synonym Names
Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein; ACTA2; ACTSA; ACTVS
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
301-375
Immunogen Sequence Length
377
OMIM
102620
3D Structure
ModBase 3D Structure for P62736
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Chicken, Cat, Dog, Guinea Pig, Hamster, Rabbit, Sheep
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Concentration
1mg/ml (lot specific)
Antigen Type
Synthetic Peptide
Antigen Source
KLH conjugated synthetic peptide derived from human Actin alpha C-terminus
Preparation and Storage
Shipped at 4 degree, Store at -20 degree  (Avoid repeated freeze/thaw cycles).
Other Notes
Small volumes of anti-ACTA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACTA2 antibody
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Applications Tested/Suitable for anti-ACTA2 antibody
Western Blot (WB)
Application Notes for anti-ACTA2 antibody
WB~~ 1:500

Western Blot (WB) of anti-ACTA2 antibody
Western blot analysis of lysate from human skeletal muscle tissue lysate,using alpha smooth muscle Actin Antibody(MBS9200862). MBS9200862 was diluted at 1:500. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
anti-ACTA2 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ACTA2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42009
NCBI Official Full Name
actin, aortic smooth muscle
NCBI Official Synonym Full Names
actin, alpha 2, smooth muscle, aorta
NCBI Official Symbol
ACTA2  [Similar Products]
NCBI Official Synonym Symbols
AAT6; ACTSA; MYMY5
  [Similar Products]
NCBI Protein Information
actin, aortic smooth muscle
UniProt Protein Name
Actin, aortic smooth muscle
UniProt Synonym Protein Names
Alpha-actin-2; Cell growth-inhibiting gene 46 protein
Protein Family
UniProt Gene Name
ACTA2  [Similar Products]
UniProt Synonym Gene Names
ACTSA; ACTVS  [Similar Products]
UniProt Entry Name
ACTA_HUMAN
NCBI Summary for ACTA2
The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
UniProt Comments for ACTA2
ACTA2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Up-regulated in response to enterovirus 71 (EV71) infection. Belongs to the actin family.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal; Contractile

Chromosomal Location of Human Ortholog: 10q23.3

Cellular Component: extracellular space; smooth muscle contractile fiber; protein complex; cytoplasm; cytosol; actin cytoskeleton

Molecular Function: protein kinase binding; ATP binding

Biological Process: muscle contraction; response to virus; regulation of blood pressure; vascular smooth muscle contraction

Disease: Moyamoya Disease 5; Multisystemic Smooth Muscle Dysfunction Syndrome; Aortic Aneurysm, Familial Thoracic 6
Product References and Citations for anti-ACTA2 antibody
Kamada S.,et al.Nucleic Acids Res. 17:1767-1767(1989).
Reddy S.,et al.J. Biol. Chem. 265:1683-1687(1990).
Kim J.W.,et al.Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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