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anti-PYY antibody :: Rabbit Peptide YY Polyclonal Antibody

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Catalog # MBS534660
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anti-PYY antibody
Product Name

Peptide YY (PYY), Polyclonal Antibody

Full Product Name

Peptide YY antibody

Product Synonym Names
Polyclonal Peptide YY; Anti-Peptide YY; PYY
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
600781
3D Structure
ModBase 3D Structure for P10082
Clonality
Polyclonal
Isotype
IgG1
Host
Rabbit
Species Reactivity
Cat, Human, Pig, Rat
Specificity
Porcine peptide YY
Form/Format
Supplied as Neat serum with 0.1% NaN3.
Biological Significance
The intestinal peptide YY is related to the PP-family of peptides and occurs in glicentin cells in the gut. They are found in the rectum, colon, ileum, and to a lower extent in the duodenum and jejunum. PYY may occur in endocrine tumors of the pancreas and the rectum.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen
Peptide YY antibody was raised in rabbit using porcine PYY as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-PYY antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PYY antibody
Rabbit polyclonal Peptide YY antibody
Product Categories/Family for anti-PYY antibody
Applications Tested/Suitable for anti-PYY antibody
Immunohistochemistry (IHC) Formalin/Paraffin
Application Notes for anti-PYY antibody
IHC-F: 1:50
IHC-P: 1:50
NCBI/Uniprot data below describe general gene information for PYY. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
10,360 Da[Similar Products]
NCBI Official Full Name
peptide YY
NCBI Official Synonym Full Names
peptide YY
NCBI Official Symbol
NCBI Official Synonym Symbols
PYY1; PYY-I
  [Similar Products]
NCBI Protein Information
peptide YY
UniProt Protein Name
Peptide YY
UniProt Synonym Protein Names
PYY-II
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
PYY_HUMAN
NCBI Summary for PYY
The protein encoded by this gene is proteolytically processed to release a peptide that inhibits pancreatic secretion and mobility in the gut. Rare variations in this gene could increase susceptibility to obesity. [provided by RefSeq, Jul 2010]
UniProt Comments for PYY
PYY: This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q21.1

Cellular Component: extracellular space; extracellular region

Molecular Function: neuropeptide hormone activity; protein binding; G-protein-coupled receptor binding; hormone activity

Biological Process: G-protein coupled receptor protein signaling pathway; cell proliferation; cell-cell signaling; eating behavior; neuropeptide signaling pathway; digestion; regulation of appetite; feeding behavior; cytoskeleton organization and biogenesis; cell motility

Disease: Obesity
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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