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anti-ADCYAP1R1 antibody :: Rabbit ADCYAP1R1 / PAC1 Receptor Polyclonal Antibody

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Catalog # MBS246921
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

ADCYAP1R1 / PAC1 Receptor, Polyclonal Antibody

Also Known As

Rabbit Polyclonal to Human ADCYAP1R1 / PAC1 Receptor

Product Synonym Names
Anti-ADCYAP1R1 / PAC1 Receptor Antibody (C-Terminus) IHC-plus; PAC1; Pac1 receptor; Pac1 receptors; PAC1-R; PACAP receptor 1; Pacap specific receptor; PACAP-R-1; PACAP/VIP receptors; PACAP1 receptor; PACAP Receptor; Pacap receptor type 1; Pacap type 1 receptor; PACAP type I receptor; PACAPR; PAC1R; Human ADCYAP1R1; PAC1 Receptor
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
468
OMIM
102981
3D Structure
ModBase 3D Structure for P41586
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bat, Gibbon, Chicken, Dog, Xenopus, Gorilla, Human, Monkey
Predicted Reactivity: Zebrafish (at least 90% immunogen sequence identity)
Specificity
Human ADCYAP1R1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from C-terminus of human ADCYAP1R1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Panda, Dog, Bat, Chicken, Lizard, Xenopus (100%).
Immunogen Type
Synthetic peptide
Immunogen
ADCYAP1R1 / PAC1 Receptor antibody was raised against synthetic 17 amino acid peptide from C-terminus of human ADCYAP1R1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Panda, Dog, Bat, Chicken, Lizard, Xenopus (100%); Stickleback, Pufferfish, Zebrafish (94%); Mouse, Rat, Hamster, Elephant, Bovine, Horse, Pig (88%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Other Notes
Small volumes of anti-ADCYAP1R1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ADCYAP1R1 antibody
The PACAP receptor type 1, a member of the vasoactive intestinal polypeptide subfamily, binds the hormone pituitary adenylate cyclase activating polypeptide (PACAP) with high affinity. PACAP is involved in stimulating the secretion of insulin, catecholamines, ACTH, and growth hormone. Additionally, PACAP appears to function as a neuromodulator/neurotransmitter in the central and peripheral nervous systems.
Applications Tested/Suitable for anti-ADCYAP1R1 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-ADCYAP1R1 antibody
IHC-P (15 ug/ml)

Immunohistochemistry (IHC) of anti-ADCYAP1R1 antibody
Anti-ADCYAP1R1 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-ADCYAP1R1 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ADCYAP1R1 antibody
Anti-ADCYAP1R1 / PAC1 Receptor antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-ADCYAP1R1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ADCYAP1R1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46,957 Da
NCBI Official Full Name
pituitary adenylate cyclase-activating polypeptide type I receptor isoform 3
NCBI Official Synonym Full Names
adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
NCBI Official Symbol
ADCYAP1R1  [Similar Products]
NCBI Official Synonym Symbols
PAC1; PAC1R; PACAPR; PACAPRI
  [Similar Products]
NCBI Protein Information
pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP-R1; PACAP receptor 1; PACAP type I receptor; pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop
UniProt Protein Name
Pituitary adenylate cyclase-activating polypeptide type I receptor
UniProt Gene Name
ADCYAP1R1  [Similar Products]
UniProt Synonym Gene Names
PACAP type I receptor; PACAP-R-1; PACAP-R1  [Similar Products]
UniProt Entry Name
PACR_HUMAN
NCBI Summary for ADCYAP1R1
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]
UniProt Comments for ADCYAP1R1
ADCYAP1R1: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. Belongs to the G-protein coupled receptor 2 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 2

Chromosomal Location of Human Ortholog: 7p14

Cellular Component: neuron projection; tight junction; cell surface; rough endoplasmic reticulum; integral to plasma membrane; plasma membrane; caveola; endosome; receptor complex

Molecular Function: ADP-ribosylation factor binding; neuropeptide binding; protein binding; vasoactive intestinal polypeptide receptor activity; receptor activity; adenylate cyclase binding

Biological Process: response to drug; development of primary female sexual characteristics; nerve growth factor receptor signaling pathway; adenylate cyclase activation; response to estradiol stimulus; G-protein coupled receptor protein signaling pathway; cAMP-mediated signaling; response to ethanol; cell surface receptor linked signal transduction; phospholipase C activation; spermatogenesis; cell differentiation; multicellular organismal response to stress; transmembrane receptor protein tyrosine kinase signaling pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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