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anti-ABCC9 antibody :: Goat ABCC9/SUR2 Polyclonal Antibody

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Catalog # MBS422891
Unit / Price
  0.1 mg  /  $225 +1 FREE 8GB USB
anti-ABCC9 antibody
Product Name

ABCC9/SUR2, Polyclonal Antibody

Also Known As

Goat anti-ABCC9/SUR2 Antibody

Product Synonym Names
ABCC9; ATP-binding cassette, sub-family C (CFTR/MRP), member 9; ABC37; CMD1O; FLJ36852; SUR2; ATP-binding cassette sub-family C member 9; ATP-binding cassette transporter sub-family C member 9; sulfonylurea receptor 2; sulfonylurea receptor 2A; ABC37 antibody; ATP-binding cassette sub-family C member 9 antibody; ATP-binding cassette transporter sub-family C member 9 antibody; ATP-binding cassette; sub-family C (CFTR/MRP); member 9 antibody; CMD1O antibody; FLJ36852 antibody; sulfonylurea receptor 2 antibody; sulfonylurea receptor 2A antibody; SUR2 antibody; ABCC9 antibody; ABCC9 / SUR2
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
Immunogen Sequence
Species Reactivity
Expected from sequence similarity: Human, Dog, Cow
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
100ug specific antibody in 200ul (lot specific)
Peptide with sequence C-TSEYSINNTGKAD, from the internal region of the protein sequence according to NP_005682.2; NP_064693.2.
Internal region
This antibody is expected to recognize isoforms SUR2A (NP_005682.2) and SUR2B (NP_064693.2).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-ABCC9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ABCC9 antibody
Peptide ELISA (EIA)
Application Notes for anti-ABCC9 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Preliminary experiments gave an approx 90kDa band in Human Testis lysates and 100kDa in Rat Testis lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 170kDa according to NP_005682.2. The 90kDa band was successfully blocked by incubation with the immunizing peptide.
NCBI/Uniprot data below describe general gene information for ABCC9. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI Related Accession #
Manufactured in an ISO 9001:2015 Certified Laboratory.NP_064693.2[Other Products]
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
174,425 Da
NCBI Official Full Name
ATP-binding cassette sub-family C member 9 isoform SUR2A
NCBI Official Synonym Full Names
ATP binding cassette subfamily C member 9
NCBI Official Symbol
ABCC9  [Similar Products]
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family C member 9
UniProt Protein Name
ATP-binding cassette sub-family C member 9
UniProt Synonym Protein Names
Sulfonylurea receptor 2
Protein Family
UniProt Gene Name
ABCC9  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
NCBI Summary for ABCC9
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]
UniProt Comments for ABCC9
ABCC9: Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation. Defects in ABCC9 are the cause of cardiomyopathy dilated type 1O (CMD1O); also known as dilated cardiomyopathy with ventricular tachycardia. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. Defects in ABCC9 are the cause of familial atrial fibrillation type 12 (ATFB12). ATFB12 is a familial form of atrial fibrillation, a common sustained cardiac rhythm disturbance. Atrial fibrillation is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure. Defects in ABCC9 are the cause of hypertrichotic osteochondrodysplasia (HTOCD). A rare disorder characterized by congenital hypertrichosis, neonatal macrosomia, a distinct osteochondrodysplasia, and cardiomegaly. The hypertrichosis leads to thick scalp hair, which extends onto the forehead, and a general increase in body hair. In addition, macrocephaly and coarse facial features, including a broad nasal bridge, epicanthal folds, a wide mouth, and full lips, can be suggestive of a storage disorder. About half of affected individuals are macrosomic and edematous at birth, whereas in childhood they usually have a muscular appearance with little subcutaneous fat. Thickened calvarium, narrow thorax, wide ribs, flattened or ovoid vertebral bodies, coxa valga, osteopenia, enlarged medullary canals, and metaphyseal widening of long bones have been reported. Cardiac manifestations such as patent ductus arteriosus, ventricular hypertrophy, pulmonary hypertension, and pericardial effusions are present in approximately 80% of cases. Motor development is usually delayed due to hypotonia. Most patients have a mild speech delay, and a small percentage have learning difficulties or intellectual disability. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Channel, potassium; Transporter; Transporter, ABC family

Chromosomal Location of Human Ortholog: 12p12.1

Cellular Component: ATP-sensitive potassium channel complex; plasma membrane; sarcolemma; sarcomere; voltage-gated potassium channel complex

Molecular Function: anion transmembrane-transporting ATPase activity; ATP binding; potassium channel activity; potassium channel regulator activity; sulfonylurea receptor activity; transporter activity

Biological Process: defense response to virus; metabolic process; potassium ion import; potassium ion transport; signal transduction; transmembrane transport

Disease: Atrial Fibrillation, Familial, 12; Cantu Syndrome; Cardiomyopathy, Dilated, 1o
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