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anti-PLXND1 antibody :: Goat Plexin D1 Polyclonal Antibody

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Catalog # MBS420760
Unit / Price
  0.1 mg  /  $300 +1 FREE 8GB USB
anti-PLXND1 antibody
Product Name

Plexin D1 (PLXND1), Polyclonal Antibody

Also Known As

Goat anti-Plexin D1 Antibody

Product Synonym Names
PLXND1; PLEXD1; KIAA0620; plexin D1; MGC75353; PLXND1 antibody; PLEXD1 antibody; KIAA0620 antibody; plexin D1 antibody; MGC75353 antibody; Plexin D1
Product Synonym Gene Name
Plexin D1[Similar Products]
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1925
Immunogen Sequence
LAEPKKSHRQ SH
OMIM
604282
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human, Mouse; Expected from sequence similarity: Human, Dog, Pig, Cow
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-LAEPKKSHRQSH, from the internal region of the protein sequence according to NP_055918.2.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-PLXND1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PLXND1 antibody
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PLXND1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Immunohistochemistry: A customer reported specific stain in Paraffin-embedded Mouse Brain after epitope retrieval in Citrate buffer pH6.
Western Blot: A customer reported a 250kDa band in Human Artherial endothelial cells lysates at 0.5ug/ml.
NCBI/Uniprot data below describe general gene information for PLXND1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
195,558 Da
NCBI Official Full Name
plexin-D1
NCBI Official Synonym Full Names
plexin D1
NCBI Official Symbol
PLXND1  [Similar Products]
NCBI Official Synonym Symbols
PLEXD1
  [Similar Products]
NCBI Protein Information
plexin-D1
UniProt Protein Name
Plexin-D1
Protein Family
UniProt Gene Name
PLXND1  [Similar Products]
UniProt Synonym Gene Names
KIAA0620  [Similar Products]
UniProt Entry Name
PLXD1_HUMAN
UniProt Comments for PLXND1
PLXND1: Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature. Mediates anti-angiogenic signaling in response to SEMA3E. Belongs to the plexin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: integral to plasma membrane; lamellipodium; plasma membrane

Molecular Function: protein binding; protein domain specific binding; semaphorin receptor activity

Biological Process: angiogenesis; branchiomotor neuron axon guidance; endothelial cell migration; patterning of blood vessels; positive regulation of protein binding; regulation of angiogenesis; regulation of axon extension involved in axon guidance; regulation of cell migration; synaptogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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