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anti-SLC6A8 antibody :: Goat Creatine transporter 1/SLC6A8 Polyclonal Antibody

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Catalog # MBS422659
Unit / Price
  0.1 mg  /  $300 +1 FREE 8GB USB
Western Blot (WB)
Product Name

Creatine transporter 1/SLC6A8, Polyclonal Antibody

Also Known As

Goat anti-Creatine transporter 1/SLC6A8 Antibody

Product Synonym Names
SLC6A8; solute carrier family 6 (neurotransmitter transporter, creatine), member 8; CRT; CRTR; CT1; MGC87396; creatine transporter 1; creatine transporter SLC6A8; sodium- and chloride-dependent creatine transporter 1; solute carrier family 6 member 8; SLC6A8 antibody; solute carrier family 6 (neurotransmitter transporter; creatine); member 8 antibody; CRT antibody; CRTR antibody; CT1 antibody; MGC87396 antibody; creatine transporter 1 antibody; creatine transporter SLC6A8 antibody; sodium- and chloride-dependent creatine transporter 1 antibody; Creatine transporter 1; Creatine transporter 1 / SLC6A8
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
Immunogen Sequence
Species Reactivity
Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
100ug specific antibody in 200ul (lot specific)
Peptide with sequence ASLANLTCDQLADRR, from the internal region of the protein sequence according to NP_005620.1; NP_001136277.1; NP_001136278.1.
Internal region
This antibody is expected to recognize all reported isoforms (NP_005620.1; NP_001136277.1; NP_001136278.1).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-SLC6A8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-SLC6A8 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-SLC6A8 antibody
Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Approx 70kDa band observed in Mouse Heart, Kidney and Skeletal Muscle lysates (calculated MW of 71. 0kDa according to Mouse NP_598748.1). Recommended concentration: 0.1-0.3ug/ml.

Western Blot (WB) of anti-SLC6A8 antibody
(0.1ug/ml) staining of Mouse Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-SLC6A8 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for SLC6A8. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI Related Accession #
Manufactured in an ISO 9001:2015 Certified Laboratory.NP_001136277.1; NP_001136278.1[Other Products]
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
58,453 Da
NCBI Official Full Name
sodium- and chloride-dependent creatine transporter 1 isoform 1
NCBI Official Synonym Full Names
solute carrier family 6 member 8
NCBI Official Symbol
SLC6A8  [Similar Products]
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
sodium- and chloride-dependent creatine transporter 1
UniProt Protein Name
Sodium- and chloride-dependent creatine transporter 1
UniProt Synonym Protein Names
Solute carrier family 6 member 8
UniProt Gene Name
SLC6A8  [Similar Products]
UniProt Synonym Gene Names
CT1; Creatine transporter 1  [Similar Products]
UniProt Entry Name
NCBI Summary for SLC6A8
The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
UniProt Comments for SLC6A8
SLC6A8: Required for the uptake of creatine in muscles and brain. Defects in SLC6A8 are the cause of X-linked creatine deficiency syndrome (XL-CDS). XL-CDS causes developmental delay, hypotonia, mental retardation, seizures, short stature and midface hypoplasia. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter, SLC family; Motility/polarity/chemotaxis; Transporter; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: creatine transporter activity; creatine:sodium symporter activity; neurotransmitter:sodium symporter activity

Biological Process: creatine metabolic process; creatine transport; muscle contraction; neurotransmitter transport; sodium ion transport; transport

Disease: Cerebral Creatine Deficiency Syndrome 1
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