• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-SNAP23 antibody :: Goat SNAP23 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS422518
Unit / Price
  0.1 mg  /  $300 +1 FREE 8GB USB
Western Blot (WB)
Product Name

SNAP23, Polyclonal Antibody

Also Known As

Goat anti-SNAP23 (aa 135-144) Antibody

Product Synonym Names
Goat Anti-SNAP23 Antibody; SNAP23; synaptosomal-associated protein, 23kDa; HsT17016; SNAP23A; SNAP23B; OTTHUMP00000161263; synaptosomal-associated protein 23; HsT17016 antibody; OTTHUMP00000161263 antibody; SNAP23A antibody; SNAP23B antibody; synaptosomal-associated protein 23 antibody; synaptosomal-associated protein; 23kDa antibody; SNAP23 antibody; SNAP23 (aa 135-144)
Antibody/Peptide Pairs
SNAP23 peptide (MBS427993) is used for blocking the activity of SNAP23 antibody (MBS422518)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
211
Immunogen Sequence
TDKADTNRDR
OMIM
602534
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow, Rabbit
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-TDKADTNRDR, from the C Terminus of the protein sequence according to NP_003816.2; NP_570710.1.
Epitope
C Terminus
Note
This antibody is expected to recognize both isoforms (NP_003816.2; NP_570710.1). Amino acid numbering in name refers to NP_003816.2 sequence.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-SNAP23 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-SNAP23 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-SNAP23 antibody
Peptide ELISA: Antibody detection limit dilution 1: 2000.
Western Blot: Approx 20+26kDa bands observed in Human Peripheral Blood Mononucleocytes lysates (calculated MW of 17.8kDa according to NP_570710.1 and of 23.4kDa according to NP_003816.2). Recommended concentration: 0.2-0.6ug/ml.

Western Blot (WB) of anti-SNAP23 antibody
(0.2ug/ml) staining of PBMC lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-SNAP23 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for SNAP23. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
Manufactured in an ISO 9001:2015 Certified Laboratory.NP_570710.1[Other Products]
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,789 Da
NCBI Official Full Name
synaptosomal-associated protein 23 isoform SNAP23A
NCBI Official Synonym Full Names
synaptosome associated protein 23kDa
NCBI Official Symbol
SNAP23  [Similar Products]
NCBI Official Synonym Symbols
SNAP-23; SNAP23A; SNAP23B; HsT17016
  [Similar Products]
NCBI Protein Information
synaptosomal-associated protein 23
UniProt Protein Name
Synaptosomal-associated protein 23
UniProt Synonym Protein Names
Vesicle-membrane fusion protein SNAP-23
UniProt Gene Name
SNAP23  [Similar Products]
UniProt Synonym Gene Names
SNAP-23  [Similar Products]
UniProt Entry Name
SNP23_HUMAN
NCBI Summary for SNAP23
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for SNAP23
SNAP23: a member of the SNAP-25 family of SNARE proteins. Structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternatively spliced isoforms have been described.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: azurophil granule; cytoplasm; focal adhesion; mast cell granule; neuron projection; nucleoplasm; plasma membrane; SNARE complex; specific granule

Molecular Function: protein binding; SNAP receptor activity; syntaxin binding

Biological Process: histamine secretion by mast cell; post-Golgi vesicle-mediated transport; protein transport; synaptic vesicle fusion to presynaptic membrane; synaptic vesicle priming; vesicle targeting
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000