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anti-GABRB2 antibody :: Goat GABRB2 Polyclonal Antibody

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Catalog # MBS421790
Unit / Price
  0.1 mg  /  $225 +1 FREE 8GB USB
anti-GABRB2 antibody
Product Name

GABRB2, Polyclonal Antibody

Popular Item
Full Product Name

Goat anti-GABRB2 Antibody

Product Synonym Names
GABRB2; gamma-aminobutyric acid (GABA) A receptor, beta 2; MGC119386; MGC119388; MGC119389; OTTHUMP00000160872; GABRB2 antibody; gamma-aminobutyric acid (GABA) A receptor; beta 2 antibody; MGC119386 antibody; MGC119388 antibody; MGC119389 antibody; OTTHUMP00000160872 antibody
Antibody/Peptide Pairs
GABRB2 peptide (MBS426270) is used for blocking the activity of GABRB2 antibody (MBS421790)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
HSFGRNALER HVAQ
OMIM
600232
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-HSFGRNALERHVAQ, from the internal region of the protein sequence according to NP_068711.1; NP_000804.1.
Epitope
Internal region
Note
This antibody is expected to recognize both reported isoforms (NP_068711.1; NP_000804.1).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-GABRB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-GABRB2 antibody
Peptide ELISA (EIA)
Application Notes for anti-GABRB2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 4000.
Western Blot: Preliminary experiments gave an approx 80kDa band in Mouse Brain lysates after 0.2 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 59.2kDa according to Human NP_068711.1 and 54.6kDa according to Mouse NP_032096.1. The 80kDa band was successfully blocked by incubation with the immunizing peptide.
NCBI/Uniprot data below describe general gene information for GABRB2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
Manufactured in an ISO 9001:2015 Certified Laboratory.NP_000804.1[Other Products]
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,741 Da
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit beta-2 isoform 1
NCBI Official Synonym Full Names
gamma-aminobutyric acid type A receptor beta2 subunit
NCBI Official Symbol
GABRB2  [Similar Products]
NCBI Protein Information
gamma-aminobutyric acid receptor subunit beta-2
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit beta-2
UniProt Synonym Protein Names
GABA(A) receptor subunit beta-2
UniProt Gene Name
GABRB2  [Similar Products]
UniProt Entry Name
GBRB2_HUMAN
NCBI Summary for GABRB2
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq, Jul 2008]
UniProt Comments for GABRB2
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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