• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-LASS5 antibody :: Goat LASS5+6/CerS5+6 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS422118
Unit / Price
  0.1 mg  /  $225 +1 FREE 8GB USB
anti-LASS5 antibody
Product Name

LASS5+6/CerS5+6, Polyclonal Antibody

Popular Item
Also Known As

Goat anti-LASS5+6/CerS5+6 Antibody

Product Synonym Names
LASS5; LAG1 homolog, ceramide synthase 5; CerS5; FLJ25304; MGC45411; Trh4; LAG1 longevity assurance homolog 5; LASS5 antibody; LAG1 homolog; ceramide synthase 5 antibody; CerS5 antibody; FLJ25304 antibody; MGC45411 antibody; Trh4 antibody; LAG1 longevity assurance homolog 5 antibody; LASS5+6 / CerS5+6
Product Synonym Gene Name
LASS5+6; CerS5+6[Similar Products]
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
392
Immunogen Sequence
RGKVSKDDRS DVES
OMIM
615335
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-RGKVSKDDRSDVES, from the internal region of the protein sequence according to NP_671723.1; NP_982288.1.
Epitope
Internal region
Note
This antibbody is expected to cross-react with the highly similar LASS6.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-LASS5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-LASS5 antibody
Peptide ELISA (EIA)
Application Notes for anti-LASS5 antibody
Peptide ELISA: Antibody detection limit dilution 1: 4000.
Western Blot: Preliminary experiments gave an approx. 60kDa band in lysates of HEK293, HeLa and HepG2 after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 45.8kDa according to NP_671723.1. The 60kDa band was successfully blocked by incubation with the immunizing peptide.
NCBI/Uniprot data below describe general gene information for LASS5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
Manufactured in an ISO 9001:2015 Certified Laboratory.NP_982288.1[Other Products]
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,259 Da
NCBI Official Full Name
ceramide synthase 5 isoform 1
NCBI Official Synonym Full Names
ceramide synthase 5
NCBI Official Symbol
CERS5  [Similar Products]
NCBI Official Synonym Symbols
Trh4; LASS5
  [Similar Products]
NCBI Protein Information
ceramide synthase 5
UniProt Protein Name
Ceramide synthase 5
UniProt Synonym Protein Names
LAG1 longevity assurance homolog 5
UniProt Gene Name
CERS5  [Similar Products]
UniProt Synonym Gene Names
LASS5; CerS5  [Similar Products]
UniProt Entry Name
CERS5_HUMAN
NCBI Summary for LASS5
This gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Comments for LASS5
LASS5: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transferase; EC 2.3.1.24; DNA-binding

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; nuclear membrane

Molecular Function: DNA binding; sphingosine N-acyltransferase activity

Biological Process: ceramide biosynthetic process; sphingolipid biosynthetic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000