• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-RGS1 antibody :: Goat RGS1/1R20 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS420870
Unit / Price
Scan QR to view Datasheet
  0.1 mg  /  $300 +1 FREE 8GB USB
Western Blot (WB)
Product Name

RGS1/1R20, Polyclonal Antibody

Full Product Name

Goat anti-RGS1/1R20 Antibody

Product Synonym Names
RGS1; 1R20; regulator of G-protein signalling 1; BL34; IER1; IR20; 1R20; Regulator of G-protein signaling 1; B-cell activation protein BL34; early response protein 1R20; immediate-early response 1, B-cell specific; RGS1 antibody; 1R20 antibody; regulator of G-protein signalling 1 antibody; BL34 antibody; IER1 antibody; IR20 antibody; 1R20 antibody; Regulator of G-protein signaling 1 antibody; B-cell activation protein BL34 antibody; early response protein 1R20 antibody; immediate-early response 1; B-cell specific antibody; RGS1 / 1R20
Product Synonym Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
NLLNDLQANS LK
OMIM
600323
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-NLLNDLQANSLK, from the C Terminus of the protein sequence according to NP_002913.3.
Epitope
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-RGS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-RGS1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-RGS1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 25kDa band seen in HepG2 lysate. Recommended for use at 0.5-2ug/ml.

Western Blot (WB) of anti-RGS1 antibody
Staining (1ug/ml) of HepG2 lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
anti-RGS1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for RGS1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,134 Da
NCBI Official Full Name
regulator of G-protein signaling 1
NCBI Official Synonym Full Names
regulator of G-protein signaling 1
NCBI Official Symbol
NCBI Official Synonym Symbols
1R20; BL34; IER1; IR20; HEL-S-87
  [Similar Products]
NCBI Protein Information
regulator of G-protein signaling 1
UniProt Protein Name
Regulator of G-protein signaling 1
UniProt Synonym Protein Names
B-cell activation protein BL34
UniProt Gene Name
UniProt Synonym Gene Names
1R20; BL34; IER1; RGS1  [Similar Products]
UniProt Entry Name
RGS1_HUMAN
NCBI Summary for RGS1
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008]
UniProt Comments for RGS1
RGS1: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 1q31

Cellular Component: cytosol; extrinsic to internal side of plasma membrane; plasma membrane

Molecular Function: calmodulin binding; G-protein alpha-subunit binding; GTPase activator activity

Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; immune response; negative regulation of signal transduction; positive regulation of GTPase activity; regulation of G-protein coupled receptor protein signaling pathway; signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000