• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-CECR2 antibody :: Goat CECR2 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS421499
Unit / Price
  0.1 mg  /  $225 +1 FREE 8GB USB
anti-CECR2 antibody
Product Name

CECR2, Polyclonal Antibody

Full Product Name

Goat anti-CECR2 Antibody

Product Synonym Names
CECR2; cat eye syndrome chromosome region, candidate 2; KIAA1740; CECR2 antibody; cat eye syndrome chromosome region; candidate 2 antibody; KIAA1740 antibody
Antibody/Peptide Pairs
CECR2 peptide (MBS426207) is used for blocking the activity of CECR2 antibody (MBS421499)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
PPHKPPTLPL DQS
OMIM
607576
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human, Dog
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-PPHKPPTLPLDQS, from the C Terminus of the protein sequence according to AAK15343.1.
Epitope
C Terminus
Note
The peptide sequence used (from AAK15343.1) differs by one residue from the RefSeq entry (XP_931107.2). It is not known whether this difference is due to a sequencing error or polymophism but the antibody is expected to recognize both sequences.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-CECR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CECR2 antibody
Peptide ELISA (EIA)
Application Notes for anti-CECR2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: No signal obtained yet but low background observed in human testis and 293 lysates at up to 1ug/ml.
NCBI/Uniprot data below describe general gene information for CECR2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
162,067 Da
NCBI Official Full Name
CECR2 protein
NCBI Official Synonym Full Names
CECR2, histone acetyl-lysine reader
NCBI Official Symbol
CECR2  [Similar Products]
NCBI Protein Information
cat eye syndrome critical region protein 2
UniProt Protein Name
Cat eye syndrome critical region protein 2
UniProt Gene Name
CECR2  [Similar Products]
UniProt Synonym Gene Names
KIAA1740  [Similar Products]
UniProt Entry Name
CECR2_HUMAN
NCBI Summary for CECR2
This gene encodes a bromodomain-containing protein that is involved in chromatin remodeling, and may additionally play a role in DNA damage response. The encoded protein functions as part of an ATP-dependent complex that is involved in neurulation. This gene is a candidate gene for Cat Eye Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
UniProt Comments for CECR2
CECR2: Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 22q11.2

Cellular Component: nucleus

Molecular Function: protein binding

Biological Process: ATP-dependent chromatin remodeling; cytokinesis; cytoskeleton organization and biogenesis; DNA fragmentation during apoptosis; neural tube development; vesicle-mediated transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-CECR2 antibody
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000