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anti-ENOX2 antibody :: Goat ENOX2/APK1 Polyclonal Antibody

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Catalog # MBS421550
Unit / Price
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  0.1 mg  /  $300 +1 FREE 8GB USB
anti-ENOX2 antibody
Product Name

ENOX2/APK1, Polyclonal Antibody

Popular Item
Full Product Name

Goat anti-ENOX2/APK1 Antibody

Product Synonym Names
ecto-NOX disulfide-thiol exchanger 2; RP5-875H3.1; APK1; COVA1; tNOX; APK1 antigen; cytosolic ovarian carcinoma antigen 1; ecto-NOX disulfide-thiol exchanger 2 antibody; RP5-875H3.1 antibody; APK1 antibody; COVA1 antibody; tNOX antibody; APK1 antigen antibody; cytosolic ovarian carcinoma antigen 1 antibody; ENOX2 / APK1
Product Synonym Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Species Reactivity
Expected from sequence similarity: Human, Dog
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
100ug specific antibody in 200ul (lot specific)
Peptide with sequence C-EKLKDDKLQVEK, from the internal region of the protein sequence according to NP_006366.2; NP_872114.1.
Internal region
This antibody is expected to recognise both reported isoforms (NP_006366.2; NP_872114.1).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-ENOX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ENOX2 antibody
Peptide ELISA (EIA)
Application Notes for anti-ENOX2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Preliminary experiments gave bands at approx 60kDa and 37kDa in Human Heart lysates after 0. 03ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 66.6kDa and 70.1kDa according to NP_006366.2 and NP_872114.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).
NCBI/Uniprot data below describe general gene information for ENOX2. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI Related Accession #
Manufactured in an ISO 9001:2015 Certified Laboratory.NP_872114.1[Other Products]
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
66,621 Da
NCBI Official Full Name
ecto-NOX disulfide-thiol exchanger 2 isoform a
NCBI Official Synonym Full Names
ecto-NOX disulfide-thiol exchanger 2
NCBI Official Symbol
ENOX2  [Similar Products]
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
ecto-NOX disulfide-thiol exchanger 2
UniProt Protein Name
Ecto-NOX disulfide-thiol exchanger 2
UniProt Synonym Protein Names
APK1 antigen; Cytosolic ovarian carcinoma antigen 1; Tumor-associated hydroquinone oxidase; tNOX
UniProt Gene Name
ENOX2  [Similar Products]
UniProt Synonym Gene Names
COVA1; tNOX  [Similar Products]
UniProt Entry Name
NCBI Summary for ENOX2
This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Comments for ENOX2
ENOX2: May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide- thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock. Belongs to the ENOX family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Cell surface; EC 1.-.-.-; Oxidoreductase

Chromosomal Location of Human Ortholog: Xq25

Cellular Component: cytosol; external side of plasma membrane; extracellular space

Molecular Function: nucleic acid binding; nucleotide binding; protein binding; protein disulfide oxidoreductase activity

Biological Process: cell growth; regulation of growth; ultradian rhythm
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