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anti-NPY2R antibody :: Rabbit NPY2R Polyclonal Antibody

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Catalog # MBS241663
Unit / Price
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  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

NPY2R, Polyclonal Antibody

Full Product Name

Rabbit Polyclonal (IgG) to Human NPY2R

Product Synonym Names
Anti-NPY2R Antibody (aa350-400) IHC-plus; NPY2R; Neuropeptide Y2 receptor; NPY-Y2 receptor; Neuropeptide Y receptor Y2; Neuropeptide y-y2; NPY2-R; Type 2 neuropeptide y receptor; Hypothalamic Y2 receptor; Neuropeptide Y receptor type 2; Peptide yy y2 receptor; Y2 receptor; Human NPY2R
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
162642
3D Structure
ModBase 3D Structure for P49146
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Dog, Human, Monkey, Mouse
Specificity
A portion of amino acids 350-400 of human NPY2-R
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.2% gelatin, 0.05% sodium azide.
Concentration
0.5 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic peptide from human NPY2R.
Immunogen Type
Synthetic peptide
Immunogen
NPY2R antibody was raised against synthetic peptide from human NPY2R.
Antigen Modification
aa350-400
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Other Notes
Small volumes of anti-NPY2R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NPY2R antibody
NPY2R belongs to the Neuropeptide Receptor GPCR family.
Applications Tested/Suitable for anti-NPY2R antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-NPY2R antibody
IHC-P (10 ug/ml), WB (1 - 3 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-NPY2R antibody
Anti-NPY2R antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-NPY2R antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-NPY2R antibody
Western blot of NPY2-R in the 1) absence and 2) presence of immunizing peptide in human kidney lysate using antibody at 0.05 ug/ml.
anti-NPY2R antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for NPY2R. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,731 Da
NCBI Official Full Name
neuropeptide Y receptor type 2
NCBI Official Synonym Full Names
neuropeptide Y receptor Y2
NCBI Official Symbol
NPY2R  [Similar Products]
NCBI Official Synonym Symbols
NPY2-R
  [Similar Products]
NCBI Protein Information
neuropeptide Y receptor type 2; NPY-Y2 receptor
UniProt Protein Name
Neuropeptide Y receptor type 2
UniProt Synonym Protein Names
NPY-Y2 receptor; Y2 receptor
Protein Family
UniProt Gene Name
NPY2R  [Similar Products]
UniProt Synonym Gene Names
NPY2-R; Y2 receptor  [Similar Products]
UniProt Entry Name
NPY2R_HUMAN
UniProt Comments for NPY2R
NPY2R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 4q31

Cellular Component: integral to plasma membrane; nonmotile primary cilium; plasma membrane

Molecular Function: peptide YY receptor activity; protein binding; calcium channel regulator activity; neuropeptide Y receptor activity; receptor activity

Biological Process: positive regulation of dopamine secretion; secretion; behavioral fear response; positive regulation of cell adhesion; negative regulation of synaptic transmission, glutamatergic; locomotory behavior; positive regulation of peptide secretion; elevation of cytosolic calcium ion concentration; negative regulation of cAMP biosynthetic process; neuropeptide signaling pathway; negative regulation of secretion; regulation of sensory perception of pain; positive regulation of smooth muscle contraction; G-protein signaling, adenylate cyclase inhibiting pathway; nitric oxide mediated signal transduction; positive regulation of circadian sleep/wake cycle, non-REM sleep; negative regulation of neurological process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-NPY2R antibody
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