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anti-NEBL antibody :: Goat NEBL/nebulette Polyclonal Antibody

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Catalog # MBS421779
Unit / Price
  0.1 mg  /  $225 +1 FREE 8GB USB
anti-NEBL antibody
Product Name

NEBL/nebulette, Polyclonal Antibody

Also Known As

Goat anti-NEBL/nebulette Antibody

Product Synonym Names
NEBL; nebulette; FLJ53769; LNEBL; MGC119746; MGC119747; bA56H7.1; LIM-nebulette; NEBL, actin-binding Z-disc protein; OTTHUMP00000019268; actin-binding Z-disk protein; NEBL antibody; nebulette antibody; FLJ53769 antibody; LNEBL antibody; MGC119746 antibody; MGC119747 antibody; bA56H7.1 antibody; LIM-nebulette antibody; NEBL; actin-binding Z-disc protein antibody; OTTHUMP00000019268 antibody; actin-binding Z-disk protein antibody; Nebulette; NEBL / nebulette
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
Immunogen Sequence
Species Reactivity
Expected from sequence similarity: Human, Mouse, Dog
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
100ug specific antibody in 200ul (lot specific)
Peptide with sequence C-ELQRLKRTQE, from the internal region of the protein sequence according to NP_998734.1; NP_001166955.1.
Internal region
This antibody is expected to recognize isoform 2 and isoform 3 (NP_998734.1; NP_001166955.1) only, but does not recognize isoform 1 (NP_006384.1).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-NEBL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-NEBL antibody
Peptide ELISA (EIA)
Application Notes for anti-NEBL antibody
Peptide ELISA: Antibody detection limit dilution 1: 4000.
Western Blot: Preliminary experiments gave an approx 30kDa band in Human Brain (Frontal Cortex) lysates, but not in Human, Mouse and Rat Heart lysates after 1ug/ml antibody staining. This protein has a calculated MW of 31.2kDa according to NP_998734.1. The 30kDa band was successfully blocked by incubation with the immunizing peptide.
NCBI/Uniprot data below describe general gene information for NEBL. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI Related Accession #
Manufactured in an ISO 9001:2015 Certified Laboratory.NP_001166955.1[Other Products]
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31,196 Da
NCBI Official Full Name
nebulette isoform 2
NCBI Official Synonym Full Names
NCBI Official Symbol
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
UniProt Protein Name
UniProt Synonym Protein Names
Actin-binding Z-disk protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
LNEBL  [Similar Products]
UniProt Entry Name
NCBI Summary for NEBL
This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
UniProt Comments for NEBL
NEBL: Binds to actin and plays an important role in the assembly of the Z-disk. Isoform 2 might play a role in the assembly of focal adhesion. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Actin-binding

Chromosomal Location of Human Ortholog: 10p12

Cellular Component: I band; stress fiber; Z disc

Molecular Function: actin filament binding; cytoskeletal protein binding; filamin binding; protein binding; structural constituent of muscle; tropomyosin binding
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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