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anti-YWHAQ antibody :: Goat 14-3-3 tau/YWHAQ Polyclonal Antibody

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Catalog # MBS420856
Unit / Price
  0.1 mg  /  $300 +1 FREE 8GB USB
Western Blot (WB)
Product Name

14-3-3 tau/YWHAQ, Polyclonal Antibody

Also Known As

Goat anti-14-3-3 tau/YWHAQ Antibody

Product Synonym Names
YWHAQ; 14-3-3 protein tau; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; 14-3-3; 1C5; HS1; 14-3-3 protein T-cell; 14-3-3 protein theta; protein tau; tyrosine 3/tryptophan 5 -monooxygenase activation protein, th; YWHAQ antibody; 14-3-3 protein tau antibody; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; theta polypeptide antibody; 14-3-3 antibody; 1C5 antibody; HS1 antibody; 14-3-3 protein T-cell antibody; 14-3-3 protein theta antibody; protein tau antibody; tyrosine 3/tryptophan 5 -monooxygenase activation protein; theta polypeptide antibody; 14-3-3 tau / YWHAQ
Product Synonym Gene Name
14-3-3 tau[Similar Products]
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
245
Immunogen Sequence
DDRKQTIDNS Q
OMIM
609009
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-DDRKQTIDNSQ, from the internal region of the protein sequence according to NP_006817.1.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-YWHAQ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-YWHAQ antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-YWHAQ antibody
Peptide ELISA: Antibody detection limit dilution 1: 4000.
Western Blot: Approx 28kDa band observed in Human Brain (Hippocampus) lysates (calculated MW of 27.8kDa according to NP_006817.1). Recommended concentration: 0. 03-0.1ug/ml.

Western Blot (WB) of anti-YWHAQ antibody
(0. 03ug/ml) staining of Human Brain (Hippocampus) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-YWHAQ antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for YWHAQ. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,764 Da
NCBI Official Full Name
14-3-3 protein theta
NCBI Official Synonym Full Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
NCBI Official Symbol
YWHAQ  [Similar Products]
NCBI Official Synonym Symbols
1C5; HS1; 14-3-3
  [Similar Products]
NCBI Protein Information
14-3-3 protein theta
UniProt Protein Name
14-3-3 protein theta
UniProt Synonym Protein Names
14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
Protein Family
UniProt Gene Name
YWHAQ  [Similar Products]
UniProt Entry Name
1433T_HUMAN
NCBI Summary for YWHAQ
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
UniProt Comments for YWHAQ
14-3-3 theta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Associates with c-BCR and BCR-Abl.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2p25.1

Cellular Component: cytoplasm; cytoplasmic vesicle membrane; cytosol; focal adhesion; membrane; mitochondrion; protein complex

Molecular Function: protein binding; protein C-terminus binding; protein domain specific binding; protein N-terminus binding

Biological Process: negative regulation of transcription, DNA-dependent; protein targeting; small GTPase mediated signal transduction; substantia nigra development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-YWHAQ antibody
 Reference Product  PubMed Publications
 BAD antibody  >1 publications with YWHAQ and BAD
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