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anti-ABCD4 antibody :: Goat ABCD4 Polyclonal Antibody

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Catalog # MBS422017
Unit / Price
  0.1 mg  /  $300 +1 FREE 8GB USB
Western Blot (WB)
Product Name

ABCD4, Polyclonal Antibody

Also Known As

Goat anti-ABCD4 Antibody

Product Synonym Names
ABCD4; ATP-binding cassette, sub-family D (ALD), member 4; ABC41; EST352188; P70R; P79R; PMP69; PXMP1L; ATP-binding cassette, sub-family D, member 4; peroxisomal membrane protein 1-like; ABCD4 antibody; ATP-binding cassette; sub-family D (ALD); member 4 antibody; ABC41 antibody; EST352188 antibody; P70R antibody; P79R antibody; PMP69 antibody; PXMP1L antibody; ATP-binding cassette; sub-family D; member 4 antibody; peroxisomal membrane protein 1-like antibody; ABCD4
Antibody/Peptide Pairs
ABCD4 peptide (MBS426038) is used for blocking the activity of ABCD4 antibody (MBS422017)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
606
Immunogen Sequence
RDDIDNPDQR ISQD
OMIM
603214
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-RDDIDNPDQRISQD, from the internal region of the protein sequence according to NP_005041.1.
Epitope
Internal region
Note
Reported variants represent identical protein: NP_064719.1 NP_064731.1 NP_064720.1 NP_064730.1
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-ABCD4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ABCD4 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-ABCD4 antibody
Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Approx 70kDa band observed in lysates of cell lines Jurkat and MOLT4 (calculated MW of 68.6kDa according to NP_005041.1). Recommended concentration: 0.3-1ug/ml.

Western Blot (WB) of anti-ABCD4 antibody
(0.3 ug/ml) staining of Jurkat lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected with chemiluminescence.
anti-ABCD4 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ABCD4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
68,597 Da
NCBI Official Full Name
ATP-binding cassette sub-family D member 4
NCBI Official Synonym Full Names
ATP binding cassette subfamily D member 4
NCBI Official Symbol
ABCD4  [Similar Products]
NCBI Official Synonym Symbols
P70R; P79R; ABC41; MAHCJ; PMP69; PXMP1L; EST352188
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family D member 4
UniProt Protein Name
ATP-binding cassette sub-family D member 4
UniProt Synonym Protein Names
PMP70-related protein; P70R; Peroxisomal membrane protein 1-like; PXMP1-L; Peroxisomal membrane protein 69; PMP69
UniProt Gene Name
ABCD4  [Similar Products]
UniProt Synonym Gene Names
PXMP1L; P70R; PXMP1-L; PMP69  [Similar Products]
UniProt Entry Name
ABCD4_HUMAN
NCBI Summary for ABCD4
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCD4
ABCD4: is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq, Jul 2008]

Protein type: Transporter; Transporter, ABC family; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: ATP-binding cassette (ABC) transporter complex; endoplasmic reticulum membrane; integral to membrane; lysosomal membrane; peroxisomal membrane; peroxisome

Molecular Function: ATP binding; ATPase activity, coupled to transmembrane movement of substances

Biological Process: cobalamin metabolic process; transmembrane transport

Disease: Methylmalonic Aciduria And Homocystinuria, Cblj Type
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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