NP_037081.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
beta-enolase
NCBI Official Synonym Full Names
enolase 3, beta, muscle
NCBI Official Synonym Symbols
NCBI Protein Information
beta-enolase
UniProt Protein Name
Beta-enolase
UniProt Synonym Protein Names
2-phospho-D-glycerate hydro-lyase; Enolase 3; Muscle-specific enolase; MSE; Skeletal muscle enolase
UniProt Synonym Gene Names
UniProt Entry Name
ENOB_RAT
UniProt Comments for Eno3
ENO3: Appears to have a function in striated muscle development and regeneration. Defects in ENO3 are the cause of glycogen storage disease type 13 (GSD13). A metabolic disorder that results in exercise-induced myalgias, generalized muscle weakness and fatigability. It is characterized by increased serum creatine kinase and decreased enolase 3 activity. Dramatically reduced protein levels with focal sarcoplasmic accumulation of glycogen- beta particles are detected on ultrastructural analysis. Belongs to the enolase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Lyase; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 4.2.1.11
Cellular Component: extracellular space; phosphopyruvate hydratase complex; membrane; cytoplasm; plasma membrane
Molecular Function: protein homodimerization activity; protein heterodimerization activity; magnesium ion binding; phosphopyruvate hydratase activity
Biological Process: response to drug; glycolysis; substantia nigra development; skeletal muscle regeneration; aging
Research Articles on Eno3
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Pathways associated with anti-Eno3 antibody
Diseases associated with anti-Eno3 antibody
Organs/Tissues associated with anti-Eno3 antibody
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