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anti-COLEC11 antibody :: Rabbit collectin sub-family member 11 Polyclonal Antibody

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Catalog # MBS713210
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-COLEC11 antibody
Product Name

collectin sub-family member 11 (COLEC11), Polyclonal Antibody

Popular Item
Also Known As

Rabbit anti-human collectin sub-family member 11 polyclonal Antibody

Product Synonym Names
collectin sub-family member 11; COLEC11; CL-K1-I; CL-K1-II; CL-K1-IIa; CL-K1-IIb; CLK1; DKFZp686N1868; MGC3279
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS713210 COA
MBS713210 Technical Datasheet
Immunogen Sequence Length
268
OMIM
612502
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Zebrafish
Purity/Purification
Antigen Affinity Purified
Immunogen
Human COLEC11
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-242495 / sc-242497
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-COLEC11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-COLEC11 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
NCBI/Uniprot data below describe general gene information for COLEC11. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,200 Da[Similar Products]
NCBI Official Full Name
Collectin sub-family member 11
NCBI Official Synonym Full Names
collectin sub-family member 11
NCBI Official Symbol
COLEC11  [Similar Products]
NCBI Official Synonym Symbols
3MC2; CLK1; CL-K1-I; CL-K1-II; CL-K1-IIa; CL-K1-IIb
  [Similar Products]
NCBI Protein Information
collectin-11; Collectin K1; collectin kidney protein 1
UniProt Protein Name
Collectin-11
UniProt Synonym Protein Names
Collectin kidney protein 1; CL-K1
Protein Family
UniProt Gene Name
COLEC11  [Similar Products]
UniProt Synonym Gene Names
CL-K1  [Similar Products]
UniProt Entry Name
COL11_HUMAN
NCBI Summary for COLEC11
This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
UniProt Comments for COLEC11
COLEC11: Lectin that binds to various sugars including fucose and mannose. Has a higher affinity for fucose compared to mannose. Does not bind to glucose, N-acetylglucosamine and N- acetylgalactosamine. Also binds lipopolysaccharides (LPS). Involved in fundamental development serving as a guidance cue for neural crest cell migration. Defects in COLEC11 are the cause of 3MC syndrome type 2 (3MC2). 3MC2 is an a disorder characterized by facial dysmorphism that includes hypertelorism, blepharophimosis, blepharoptosis and highly archedDE eyebrows, cleft lip and/or palate, craniosynostosis, learning disability and genital, limb and vesicorenal anomalies. The term 3MC syndrome includes Carnevale, Mingarelli, Malpuech, and Michels syndromes. Belongs to the COLEC10/COLEC11 family. 9 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 2p25.3

Cellular Component: collagen; extracellular region

Molecular Function: mannose binding

Biological Process: receptor-mediated endocytosis; multicellular organismal development; developmental process

Disease: 3mc Syndrome 2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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