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anti-C4.4A antibody :: Rabbit C4.4A / LYPD3 Polyclonal Antibody

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Catalog # MBS241518
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

C4.4A / LYPD3, Polyclonal Antibody

Full Product Name

Rabbit Polyclonal to Human C4.4A / LYPD3

Product Synonym Names
Anti-C4.4A / LYPD3 Antibody (C-Terminus) IHC-plus; LYPD3; C4.4A; MIG-C4; LY6/PLAUR domain containing 3; Human C4.4A; LYPD3
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
609484
3D Structure
ModBase 3D Structure for O95274
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human
Specificity
Human LYPD3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic 13 amino acid peptide from C-terminus of human LYPD3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Panda (92%); Mouse, Rat, Horse (85%).
Immunogen Type
Synthetic peptide
Immunogen
C4.4A / LYPD3 antibody was raised against synthetic 13 amino acid peptide from C-terminus of human LYPD3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Panda (92%); Mouse, Rat, Horse (85%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Other Notes
Small volumes of anti-C4.4A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-C4.4A antibody
C4.4A is a structural homolog of the urokinase-type plasminogen activator receptor (uPAR). It was originally identified as a metastasis-associated membrane protein in malignant urothelium. In literature IHC studies, staining has been observed in suprabasal keratinocytes of chronic wounds and the amniotic membrane of placenta. ISH analysis demonstrated expression in urothelium of the ureter.
Applications Tested/Suitable for anti-C4.4A antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-C4.4A antibody
IHC-P (15 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-C4.4A antibody
Anti-LYPD3 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-C4.4A antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-C4.4A antibody
Anti-LYPD3 antibody IHC of human skin, hair follicle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-C4.4A antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for C4.4A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
35,971 Da
NCBI Official Full Name
ly6/PLAUR domain-containing protein 3
NCBI Official Synonym Full Names
LY6/PLAUR domain containing 3
NCBI Official Symbol
LYPD3  [Similar Products]
NCBI Official Synonym Symbols
C4.4A
  [Similar Products]
NCBI Protein Information
ly6/PLAUR domain-containing protein 3; MIG-C4; 2310061G07Rik; matrigel-induced gene C4 protein; GPI-anchored metastasis-associated protein homolog; GPI-anchored metastasis-associated protein C4.4A homolog
UniProt Protein Name
Ly6/PLAUR domain-containing protein 3
UniProt Synonym Protein Names
GPI-anchored metastasis-associated protein C4.4A homolog; Matrigel-induced gene C4 protein; MIG-C4
UniProt Gene Name
LYPD3  [Similar Products]
UniProt Synonym Gene Names
C4.4A; MIG-C4  [Similar Products]
UniProt Entry Name
LYPD3_HUMAN
UniProt Comments for C4.4A
LYPD3: Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression.

Protein type: Membrane protein, GPI anchor; Motility/polarity/chemotaxis; Cell adhesion

Chromosomal Location of Human Ortholog: 19q13.31

Cellular Component: extracellular space; anchored to plasma membrane; integral to membrane

Molecular Function: laminin binding

Biological Process: cell-matrix adhesion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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