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anti-EMR1 antibody :: Rabbit EMR1 / F4/80 Polyclonal Antibody

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Catalog # MBS243528
Unit / Price
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  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

EMR1 / F4/80, Polyclonal Antibody

Full Product Name

Rabbit Polyclonal to Human EMR1 / F4/80

Product Synonym Names
Anti-EMR1 / F4/80 Antibody (N-Terminus) IHC-plus; EMR1; EMR1 hormone receptor; F4/80; EGF-like module receptor 1; TM7LN3; Human EMR1; F4/80
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
600493
3D Structure
ModBase 3D Structure for Q14246
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Predicted Reactivity: Gorilla, Gibbon (at least 90% immunogen sequence identity)
Specificity
Human EMR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human EMR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (93%); Monkey (87%); Marmoset, Mouse, Rat, Pig, Platypus (80%).
Immunogen Type
Synthetic peptide
Immunogen
EMR1 / F4/80 antibody was raised against synthetic 16 amino acid peptide from N-terminal extracellular domain of human EMR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (93%); Monkey (87%); Marmoset, Mouse, Rat, Pig, Platypus (80%).
Antigen Modification
N-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Other Notes
Small volumes of anti-EMR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-EMR1 antibody
EGF-Like Module Containing Mucin-Like Hormone Receptor-Like Sequence 1 (EMR1) is characterized as an Orphan-B GPCR with an unknown ligand. The C-terminus contains seven hydrophobic segments, characteristic of a G protein-coupled receptor. The N-terminus of EMR1 has 6 EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties.
Product Categories/Family for anti-EMR1 antibody
Applications Tested/Suitable for anti-EMR1 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-EMR1 antibody
IHC-P (10 - 20 ug/ml)

Immunohistochemistry (IHC) of anti-EMR1 antibody
Anti-EMR1 / F4/80 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-EMR1 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-EMR1 antibody
Anti-EMR1 / F4/80 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-EMR1 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-EMR1 antibody
Anti-EMR1 antibody IHC of human bone marrow. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-EMR1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for EMR1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
82,771 Da
NCBI Official Full Name
EGF-like module-containing mucin-like hormone receptor-like 1 isoform 1
NCBI Official Synonym Full Names
egf-like module containing, mucin-like, hormone receptor-like 1
NCBI Official Symbol
NCBI Official Synonym Symbols
TM7LN3
  [Similar Products]
NCBI Protein Information
EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; EGF-like module receptor 1; egf-like module containing, mucin-like, hormone receptor-like sequence 1
UniProt Protein Name
EGF-like module-containing mucin-like hormone receptor-like 1
UniProt Synonym Protein Names
EGF-like module receptor 1; EMR1 hormone receptor
UniProt Gene Name
UniProt Synonym Gene Names
TM7LN3  [Similar Products]
UniProt Entry Name
EMR1_HUMAN
NCBI Summary for EMR1
This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
UniProt Comments for EMR1
EMR1: Could be involved in cell-cell interactions. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; GPCR, family 2; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: integral to plasma membrane; external side of plasma membrane

Molecular Function: G-protein coupled receptor activity; calcium ion binding

Biological Process: G-protein coupled receptor protein signaling pathway; cell adhesion
Precautions
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Disclaimer
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