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anti-LTB4R antibody :: Rabbit Leukotriene B4 Receptor / BLT1 Polyclonal Antibody

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Catalog # MBS246847
Unit / Price
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  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

Leukotriene B4 Receptor / BLT1 (LTB4R), Polyclonal Antibody

Full Product Name

Rabbit Polyclonal to Human Leukotriene B4 Receptor / BLT1

Product Synonym Names
Anti-Leukotriene B4 Receptor / BLT1 Antibody (C-Terminus) IHC-plus; BLT; BLTR; Blt-1; Chemokine receptor-like 1; G protein-coupled receptor 16; GPR16; Leukotriene B4 receptor; Leukotriene B4 receptor 1; G-protein coupled receptor 16; LTBR1; p2Y purinoceptor 7; p2Y7; LTB4-R 1; p2RY7; CMKRL1; LTB4-R1; LTB4R1; Human Leukotriene B4 Receptor; BLT1
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
601531
3D Structure
ModBase 3D Structure for Q15722
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human, Monkey
Specificity
Human Leukotriene B4 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from C-terminus of human Leukotriene B4 Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Mouse, Rat, Horse, Opossum (88%).
Immunogen Type
Synthetic peptide
Immunogen
Leukotriene B4 Receptor / BLT1 antibody was raised against synthetic 16 amino acid peptide from C-terminus of human Leukotriene B4 Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Mouse, Rat, Horse, Opossum (88%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Other Notes
Small volumes of anti-LTB4R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-LTB4R antibody
BLT1 is a Chemoattractant Receptor that binds the potent chemoattractant leukotriene B4 (LTB4) which is involved in defense against infection. Leukotriene B4 also activates the transcription factor PPAR alpha, resulting in the activation of genes that terminate inflammatory processes (Yokomizo et al., 1997). Although BLT1 shows homology to other P2Y receptors, it does not function as a purinoreceptor (Yokomizo et al., 1997).
Applications Tested/Suitable for anti-LTB4R antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-LTB4R antibody
IHC-P (4 ug/ml)

Immunohistochemistry (IHC) of anti-LTB4R antibody
Anti-Leukotriene B4 Receptor antibody IHC of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-LTB4R antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-LTB4R antibody
Anti-Leukotriene B4 Receptor / BLT1 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-LTB4R antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for LTB4R. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,557 Da
NCBI Official Full Name
leukotriene B4 receptor 1
NCBI Official Synonym Full Names
leukotriene B4 receptor
NCBI Official Symbol
LTB4R  [Similar Products]
NCBI Official Synonym Symbols
BLT1; BLTR; P2Y7; GPR16; LTBR1; P2RY7; CMKRL1; LTB4R1
  [Similar Products]
NCBI Protein Information
leukotriene B4 receptor 1; LTB4-R1; LTB4-R 1; P2Y purinoceptor 7; chemokine receptor-like 1; G protein-coupled receptor 16; G-protein coupled receptor 16; chemoattractant receptor-like 1; purinergic receptor P2Y, G-protein coupled, 7
UniProt Protein Name
Leukotriene B4 receptor 1
UniProt Synonym Protein Names
Chemoattractant receptor-like 1; G-protein coupled receptor 16; P2Y purinoceptor 7; P2Y7
Protein Family
UniProt Gene Name
LTB4R  [Similar Products]
UniProt Synonym Gene Names
BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7; LTB4-R 1; LTB4-R1; P2Y7  [Similar Products]
UniProt Entry Name
LT4R1_HUMAN
UniProt Comments for LTB4R
LTB4R: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 14q11.2-q12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: leukotriene B4 receptor activity; nucleotide binding; leukotriene receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; muscle contraction; immune response; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); cell motility; inflammatory response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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