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anti-FFAR2 antibody :: Rabbit FFAR2 / GPR43 Polyclonal Antibody

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Catalog # MBS240941
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

FFAR2 / GPR43, Polyclonal Antibody

Also Known As

Rabbit Polyclonal to Human FFAR2 / GPR43

Product Synonym Names
Anti-FFAR2 / GPR43 Antibody (Extracellular Domain) IHC-plus; FFAR2; FFA2R; Free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43; LSSIG; GPR43; Gpcr43; Human FFAR2; GPR43
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
330
OMIM
603823
3D Structure
ModBase 3D Structure for O15552
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gorilla, Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
Specificity
Human GPR43. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FFAR3 (47%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from 2nd extracellular domain of human GPR43. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (94%); Mouse, Rat, Dog, Panda, Rabbit, Pig (88%); Horse, Opossum (82%).
Immunogen Type
Synthetic peptide
Immunogen
FFAR2 / GPR43 antibody was raised against synthetic 17 amino acid peptide from 2nd extracellular domain of human GPR43. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (94%); Mouse, Rat, Dog, Panda, Rabbit, Pig (88%); Horse, Opossum (82%).
Antigen Modification
Extracellular Domain
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Other Notes
Small volumes of anti-FFAR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FFAR2 antibody
GPR43 is classified as a Carboxylic Acid GPCR. The location of this receptor in the immune system is suggestive of potential roles in immune cell function and hematopoiesis.
Applications Tested/Suitable for anti-FFAR2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-FFAR2 antibody
IHC-P (35 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-FFAR2 antibody
Anti-FFAR2 / GPR43 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-FFAR2 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-FFAR2 antibody
Anti-FFAR2 / GPR43 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-FFAR2 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-FFAR2 antibody
Anti-GPR43 antibody IHC of human lung, alveolar macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-FFAR2 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-FFAR2 antibody
Anti-FFAR2 / GPR43 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-FFAR2 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for FFAR2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,144 Da
NCBI Official Full Name
free fatty acid receptor 2
NCBI Official Synonym Full Names
free fatty acid receptor 2
NCBI Official Symbol
FFAR2  [Similar Products]
NCBI Official Synonym Symbols
FFA2R; GPR43
  [Similar Products]
NCBI Protein Information
free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43; free fatty acid activated receptor 2
UniProt Protein Name
Free fatty acid receptor 2
UniProt Synonym Protein Names
G-protein coupled receptor 43
Protein Family
UniProt Gene Name
FFAR2  [Similar Products]
UniProt Synonym Gene Names
FFA2; GPCR43; GPR43  [Similar Products]
UniProt Entry Name
FFAR2_HUMAN
NCBI Summary for FFAR2
This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. [provided by RefSeq, Apr 2009]
UniProt Comments for FFAR2
FFAR2: Receptor for short chain fatty acids through a G(i)- protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: cell projection; integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding; lipid binding

Biological Process: fat cell differentiation; G-protein coupled receptor protein signaling pathway; sequestering of lipid; mucosal immune response; regulation of acute inflammatory response; positive regulation of cytokine production during immune response; cell surface pattern recognition receptor signaling pathway; positive regulation of acute inflammatory response to non-antigenic stimulus; glucose homeostasis; leukocyte chemotaxis during inflammatory response; positive regulation of chemokine production
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-FFAR2 antibody
Organs/Tissues associated with anti-FFAR2 antibody
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