• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-OASIS antibody :: Goat OASIS / CREB3L1 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS244171
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

OASIS / CREB3L1, Polyclonal Antibody

Also Known As

Goat Polyclonal to Human OASIS / CREB3L1

Product Synonym Names
Anti-OASIS / CREB3L1 Antibody (C-Terminus) IHC-plus; CREB3L1; BBF-2 homolog; OASIS; Human OASIS; CREB3L1
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
519
3D Structure
ModBase 3D Structure for Q96BA8
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gorilla, Human, Monkey
Specificity
Human CREB3L1.
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Concentration
0.5 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic peptide C-DFSHSKEWFHDRD from the C-terminus of human CREB3L1 (NP_443086.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%); Rat, Hamster, Elephant, Bovine, Bat, Pig (85%).
Immunogen Type
Synthetic peptide
Immunogen
OASIS / CREB3L1 antibody was raised against synthetic peptide C-DFSHSKEWFHDRD from the C-terminus of human CREB3L1 (NP_443086.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%); Rat, Hamster, Elephant, Bovine, Bat, Pig (85%).
Antigen Modification
C-Terminus
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Other Notes
Small volumes of anti-OASIS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-OASIS antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-OASIS antibody
ELISA (1:32000), IHC-P (3.75 ug/ml), WB (1 - 3 ug/ml)

Immunohistochemistry (IHC) of anti-OASIS antibody
Anti-CREB3L1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
anti-OASIS antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-OASIS antibody
Anti-CREB3L1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
anti-OASIS antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-OASIS antibody
Approx. 60 kD band observed in lysates of cell line A549 (calculated MW of 57 kD according to NP_443086.1).
anti-OASIS antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for OASIS. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,783 Da
NCBI Official Full Name
cyclic AMP-responsive element-binding protein 3-like protein 1
NCBI Official Synonym Full Names
cAMP responsive element binding protein 3-like 1
NCBI Official Symbol
CREB3L1  [Similar Products]
NCBI Official Synonym Symbols
OASIS
  [Similar Products]
NCBI Protein Information
cyclic AMP-responsive element-binding protein 3-like protein 1; BBF-2 homolog; old astrocyte specifically-induced substance; cAMP-responsive element-binding protein 3-like protein 1
UniProt Protein Name
Cyclic AMP-responsive element-binding protein 3-like protein 1
UniProt Synonym Protein Names
Old astrocyte specifically-induced substance; OASIS
UniProt Gene Name
CREB3L1  [Similar Products]
UniProt Synonym Gene Names
OASIS; cAMP-responsive element-binding protein 3-like protein 1; OASIS  [Similar Products]
UniProt Entry Name
CR3L1_HUMAN
NCBI Summary for OASIS
The protein encoded by this gene is normally found in the membrane of the endoplasmic reticulum (ER). However, upon stress to the ER, the encoded protein is cleaved and the released cytoplasmic transcription factor domain translocates to the nucleus. There it activates the transcription of target genes by binding to box-B elements. [provided by RefSeq, Jun 2013]
UniProt Comments for OASIS
CREB3L1: Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE. Belongs to the bZIP family. ATF subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transcription factor

Chromosomal Location of Human Ortholog: 11p11.2

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane; nucleus

Molecular Function: sequence-specific DNA binding; chromatin binding

Biological Process: transcription, DNA-dependent; unfolded protein response; regulation of bone mineralization
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-OASIS antibody
 Reference Product  PubMed Publications
 CREB3L3 antibody  >3 publications with OASIS and CREB3L3
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000