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anti-PHPT1 antibody :: Rabbit anti-Human 14 kDa phosphohistidine phosphatase Polyclonal Antibody

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Catalog # MBS1491309
Unit / Price
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  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
anti-PHPT1 antibody
Product Name

14 kDa phosphohistidine phosphatase (PHPT1), Polyclonal Antibody

Full Product Name

Rabbit anti-human 14 kDa phosphohistidine phosphatase polyclonal Antibody, HRP conjugated

Product Synonym Names
Phosphohistidine phosphatase 1 Protein janus-A homolog PHPT1 PHP14 CGI-202; HSPC141
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
610167
3D Structure
ModBase 3D Structure for Q9NRX4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
HRP
Immunogen
Recombinant human 14 kDa phosphohistidine phosphatase protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-163229 / sc-130229
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-PHPT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PHPT1 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for PHPT1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
13,672 Da[Similar Products]
NCBI Official Full Name
14 kDa phosphohistidine phosphatase isoform 2
NCBI Official Synonym Full Names
phosphohistidine phosphatase 1
NCBI Official Symbol
PHPT1  [Similar Products]
NCBI Official Synonym Symbols
PHP14; CGI-202; HSPC141; HEL-S-132P
  [Similar Products]
NCBI Protein Information
14 kDa phosphohistidine phosphatase
UniProt Protein Name
14 kDa phosphohistidine phosphatase
UniProt Synonym Protein Names
Phosphohistidine phosphatase 1; Protein janus-A homolog
UniProt Gene Name
PHPT1  [Similar Products]
UniProt Synonym Gene Names
PHP14  [Similar Products]
UniProt Entry Name
PHP14_HUMAN
NCBI Summary for PHPT1
This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
UniProt Comments for PHPT1
PHPT1: a phosphohistidine phosphatase. Present preferentially in heart and skeletal muscle. Insensitive to inhibition by okadaic acid and EDTA.

Protein type: Cofactor and Vitamin Metabolism - riboflavin; Phosphatase; EC 3.1.3.-; Cofactor and Vitamin Metabolism - thiamine; Motility/polarity/chemotaxis; Carbohydrate Metabolism - fructose and mannose

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: cytosol

Molecular Function: calcium channel inhibitor activity; phosphohistidine phosphatase activity; phosphoprotein phosphatase activity

Biological Process: negative regulation of lyase activity; negative regulation of T cell receptor signaling pathway; protein amino acid dephosphorylation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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