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anti-DAP3 antibody :: Rabbit anti-Human 28S ribosomal protein S29 Polyclonal Antibody

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Catalog # MBS1493778
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

28S ribosomal protein S29 (DAP3), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti-human 28S ribosomal protein S29, mitochondrial polyclonal Antibody(DAP3)

Product Synonym Names
MRP-S29; S29mt; Death-associated protein 3; DAP-3; Ionizing radiation resistance conferring protein; DAP3; MRPS29
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
602074
3D Structure
ModBase 3D Structure for P51398
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human 28S ribosomal protein S29, mitochondrial protein (159-398aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-14099
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-DAP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DAP3 antibody
Involved in mediating interferon-gamma-induced cell death.
Applications Tested/Suitable for anti-DAP3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-DAP3 antibody
Recommended dilution: WB:1:500-2000
IHC:1:20-1:200

Western Blot (WB) of anti-DAP3 antibody
All lanes: 28S ribosomal protein S29, mitochondrial antibody at 10ug/ml
Lane 1:Hela whole cell lysate
Lane 2:293T whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 46,42 kDa
Observed band size: 46 kDa

anti-DAP3 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-DAP3 antibody
Immunohistochemistry of paraffin-embedded human breast cancer using MBS1493778 at dilution 1:100
anti-DAP3 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for DAP3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,673 Da
NCBI Official Full Name
28S ribosomal protein S29, mitochondrial isoform 1
NCBI Official Synonym Full Names
death associated protein 3
NCBI Official Symbol
NCBI Official Synonym Symbols
DAP-3; MRPS29; MRP-S29; bMRP-10
  [Similar Products]
NCBI Protein Information
28S ribosomal protein S29, mitochondrial
UniProt Protein Name
28S ribosomal protein S29, mitochondrial
UniProt Synonym Protein Names
Death-associated protein 3; DAP-3; Ionizing radiation resistance conferring protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
MRPS29; MRP-S29; S29mt; DAP-3  [Similar Products]
UniProt Entry Name
RT29_HUMAN
NCBI Summary for DAP3
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Dec 2010]
UniProt Comments for DAP3
DAP3: Involved in mediating interferon-gamma-induced cell death. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Nuclear receptor co-regulator; Mitochondrial

Chromosomal Location of Human Ortholog: 1q22

Cellular Component: mitochondrial inner membrane; mitochondrial small ribosomal subunit; mitochondrion; nucleoplasm

Molecular Function: protein binding; structural constituent of ribosome

Biological Process: apoptotic mitochondrial changes; mitochondrial translation; organelle organization and biogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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