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anti-ADAM9 antibody :: Rabbit anti-Human A Disintegrin And Metalloprotease 9 (ADAM9) Polyclonal Antibody

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Catalog # MBS2005040 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $105 +1 FREE 8GB USB
  0.02 mg  /  $125 +1 FREE 8GB USB
  0.05 mg  /  $170 +1 FREE 8GB USB
  0.1 mg  /  $220 +1 FREE 8GB USB
  0.2 mg  /  $320 +1 FREE 8GB USB
  1 mg  /  $760 +1 FREE 8GB USB
Product Name

A Disintegrin And Metalloprotease 9 (ADAM9), Polyclonal Antibody

Popular Item
Also Known As

Polyclonal Antibody to A Disintegrin And Metalloprotease 9 (ADAM9)

Matching Pairs
Unconjugated Antibody: A Disintegrin And Metalloprotease 9 (ADAM9) (MBS2005040)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
Matching Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1935
Immunogen Sequence
Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG S-P CCEGSTCKLK SFAECAYGDC CKDCRFLPGG TLCRGKTSEC DVPEYCNGSS QFCQPDVFIQ NGYPCQNNKA YCYNGMCQYY DAQCQVIFGS KAKAAPKDCF IEVNSKGDRF GNCGFSGNEY KKCATGNALC GKLQCENVQE IPVFGIVPAI IQTPSRGTKC WGVDFQLGSD VPDPGMVNEG TKCGAGKICR NFQCVDASVL NYDCDVQKKC HGHGVCNSNK NCHCENGWAP PNCETKGYGG
OMIM
U41766 mRNA
3D Structure
ModBase 3D Structure for Q13443
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
The antibody is a rabbit polyclonal antibody raised against ADAM9. It has been selected for its ability to recognize ADAM9 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Concentration
200ug/ml (lot specific)
Immunogen
Recombinant ADAM9 (Pro440~Gly680) expressed in E.coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2059637
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Other Notes
Small volumes of anti-ADAM9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ADAM9 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-ADAM9 antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-ADAM9 antibody
Western Blot: Sample: Recombinant protein.
anti-ADAM9 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ADAM9 antibody
DAB staining on IHC-P; Samples: Human Kidney Tissue)
anti-ADAM9 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ADAM9. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
72,359 Da
NCBI Official Full Name
disintegrin and metalloproteinase domain-containing protein 9
NCBI Official Synonym Full Names
ADAM metallopeptidase domain 9
NCBI Official Symbol
ADAM9  [Similar Products]
NCBI Official Synonym Symbols
MCMP; MDC9; CORD9; Mltng
  [Similar Products]
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 9
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 9
UniProt Synonym Protein Names
Cellular disintegrin-related protein; Meltrin-gamma; Metalloprotease/disintegrin/cysteine-rich protein 9; Myeloma cell metalloproteinase
UniProt Gene Name
ADAM9  [Similar Products]
UniProt Synonym Gene Names
KIAA0021; MCMP; MDC9; MLTNG; ADAM 9  [Similar Products]
NCBI Summary for ADAM9
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010]
UniProt Comments for ADAM9
ADAM9: Probable zinc protease. May mediate cell-cell or cell- matrix interactions. Isoform 2 displays alpha-secretase activity for APP. Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.24.-; Membrane protein, integral; Motility/polarity/chemotaxis; Protease

Chromosomal Location of Human Ortholog: 8p11.22

Cellular Component: basolateral plasma membrane; cell surface; extracellular exosome; extracellular space; focal adhesion; integral component of membrane

Molecular Function: collagen binding; integrin binding; laminin binding; metal ion binding; metalloendopeptidase activity; metallopeptidase activity; protein binding; protein kinase C binding; SH3 domain binding

Biological Process: activation of MAPKK activity; cell adhesion; cell adhesion mediated by integrin; cell migration; cell-cell adhesion mediated by integrin; cell-matrix adhesion; integrin-mediated signaling pathway; keratinocyte differentiation; membrane protein ectodomain proteolysis; monocyte activation; PMA-inducible membrane protein ectodomain proteolysis; positive regulation of cell adhesion mediated by integrin; positive regulation of keratinocyte migration; positive regulation of membrane protein ectodomain proteolysis; positive regulation of protein secretion; response to calcium ion; response to glucocorticoid stimulus; response to hydrogen peroxide; response to laminar fluid shear stress; response to manganese ion; response to tumor necrosis factor; transforming growth factor beta receptor signaling pathway

Disease: Cone-rod Dystrophy 9
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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