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anti-AKAP1 antibody :: Rabbit anti-Human A kinase (PRKA) anchor protein 1 Polyclonal Antibody

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Catalog # MBS713883
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-AKAP1 antibody
Product Name

A kinase (PRKA) anchor protein 1 (AKAP1), Polyclonal Antibody

Full Product Name

Rabbit anti-human A kinase (PRKA) anchor protein 1 polyclonal Antibody

Product Synonym Names
A kinase (PRKA) anchor protein 1; AKAP1; AKAP; AKAP121; AKAP149; AKAP84; D-AKAP1; MGC1807; PRKA1; SAKAP84
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
602449
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Immunogen
Human AKAP1
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-6439 / sc-33576
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-AKAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-AKAP1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
NCBI/Uniprot data below describe general gene information for AKAP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
62,921 Da[Similar Products]
NCBI Official Full Name
A-kinase anchor protein 1, mitochondrial
NCBI Official Synonym Full Names
A kinase (PRKA) anchor protein 1
NCBI Official Symbol
AKAP1  [Similar Products]
NCBI Official Synonym Symbols
AKAP; PRKA1; AKAP84; TDRD17; AKAP121; AKAP149; D-AKAP1; PPP1R43; SAKAP84
  [Similar Products]
NCBI Protein Information
A-kinase anchor protein 1, mitochondrial; AKAP 149; D-AKAP-1; protein kinase A1; tudor domain containing 17; A-kinase anchor protein 149 kDa; protein kinase A anchoring protein 1; spermatid A-kinase anchor protein 84; protein phosphatase 1, regulatory subunit 43; dual-specificity A-kinase anchoring protein 1
UniProt Protein Name
A-kinase anchor protein 1, mitochondrial
UniProt Synonym Protein Names
A-kinase anchor protein 149 kDa; AKAP 149; Dual specificity A-kinase-anchoring protein 1; D-AKAP-1; Protein kinase A-anchoring protein 1; PRKA1; Spermatid A-kinase anchor protein 84; S-AKAP84
Protein Family
UniProt Gene Name
AKAP1  [Similar Products]
UniProt Synonym Gene Names
AKAP149; PRKA1; AKAP 149; D-AKAP-1; PRKA1; S-AKAP84  [Similar Products]
UniProt Entry Name
AKAP1_HUMAN
NCBI Summary for AKAP1
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment. [provided by RefSeq, Jul 2008]
UniProt Comments for AKAP1
AKAP1: Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane. AKAP149 is highly expressed in prostate and small intestine whereas S-AKAP84 is expressed in kidney, pancreas, liver, lung and brain. AKAP149 is also expressed in colon carcinoma. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; RNA-binding; Mitochondrial; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 17q22

Cellular Component: mitochondrial outer membrane; membrane; mitochondrion; integral to membrane; cytosol

Molecular Function: protein binding; RNA binding

Biological Process: blood coagulation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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