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anti-A4GALT antibody :: Rabbit anti-Human A4GALT Polyclonal Antibody

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Catalog # MBS9205451
Unit / Price
  0.08 mL  /  $150 +1 FREE 8GB USB
  0.4 mL  /  $340 +1 FREE 8GB USB
Western Blot (WB)
Product Name

A4GALT, Polyclonal Antibody

Also Known As

A4GALT Antibody (N-term)

Product Synonym Names
Lactosylceramide 4-alpha-galactosyltransferase; Alpha-1,4-N-acetylglucosaminyltransferase; Alpha-1,4-galactosyltransferase; Alpha4Gal-T1; CD77 synthase; Globotriaosylceramide synthase; Gb3 synthase; P1/Pk synthase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase; A4GALT; A14GALT; A4GALT1
Antibody/Peptide Pairs
A4GALT peptide (MBS9217428) is used for blocking the activity of A4GALT antibody (MBS9205451)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
26-54
Immunogen Sequence Length
353
OMIM
111400
3D Structure
ModBase 3D Structure for Q9NPC4
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human
Specificity
This A4GALT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human A4GALT.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.29 (lot specific)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-A4GALT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-A4GALT antibody
The protein encoded by this gene catalyzes the transfer of
galactose to lactosylceramide to form globotriaosylceramide, which
has been identified as the P(k) antigen of the P blood group
system. The encoded protein, which is a type II membrane protein
found in the Golgi, is also required for the synthesis of the
bacterial verotoxins receptor.
Product Categories/Family for anti-A4GALT antibody
Applications Tested/Suitable for anti-A4GALT antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-A4GALT antibody
WB~~1:1000

Western Blot (WB) of anti-A4GALT antibody
A4GALT Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the A4GALT antibody detected the A4GALT protein (arrow).
anti-A4GALT antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for A4GALT. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40499
NCBI Official Full Name
lactosylceramide 4-alpha-galactosyltransferase
NCBI Official Synonym Full Names
alpha 1,4-galactosyltransferase
NCBI Official Symbol
A4GALT  [Similar Products]
NCBI Official Synonym Symbols
P1; PK; Gb3S; P(k); P1PK; A14GALT; A4GALT1
  [Similar Products]
NCBI Protein Information
lactosylceramide 4-alpha-galactosyltransferase
UniProt Protein Name
Lactosylceramide 4-alpha-galactosyltransferase
UniProt Synonym Protein Names
Alpha-1,4-N-acetylglucosaminyltransferase; Alpha-1,4-galactosyltransferase; Alpha4Gal-T1; CD77 synthase; Globotriaosylceramide synthase; Gb3 synthase; P1/Pk synthase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
UniProt Gene Name
A4GALT  [Similar Products]
UniProt Synonym Gene Names
A14GALT; A4GALT1; Gb3 synthase  [Similar Products]
UniProt Entry Name
A4GAT_HUMAN
NCBI Summary for A4GALT
The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. [provided by RefSeq, Jul 2008]
UniProt Comments for A4GALT
A4GALT: Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins. Belongs to the glycosyltransferase 32 family.

Protein type: Glycan Metabolism - glycosphingolipid biosynthesis - globo series; Transferase; EC 2.4.1.228; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q13.2

Cellular Component: membrane; integral to Golgi membrane

Molecular Function: toxin binding; galactosyltransferase activity; lactosylceramide 4-alpha-galactosyltransferase activity

Biological Process: globoside biosynthetic process; glycosphingolipid biosynthetic process; plasma membrane organization and biogenesis; protein amino acid glycosylation

Disease: Blood Group, P1pk System
Product References and Citations for anti-A4GALT antibody
Zumbrun, S.D., et al. Infect. Immun. 78(11):4488-4499(2010)
Shin, I.S., et al. BMB Rep 42(5):310-314(2009)
Lund, N., et al. Blood 113(20):4980-4991(2009)
Okuda, T., et al. Glycobiology 18(12):1028-1035(2008)
Hellberg, A., et al. BMC Genet. 6, 49 (2005) :

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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