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anti-SLC7A10 antibody :: Rabbit anti-Human AAA1 Polyclonal Antibody

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Catalog # MBS9211271
Unit / Price
  0.08 mL  /  $150 +1 FREE 8GB USB
  0.4 mL  /  $340 +1 FREE 8GB USB
Product Name

AAA1 (SLC7A10), Polyclonal Antibody

Also Known As

AAA1 Antibody (C-term)

Product Synonym Names
Asc-type amino acid transporter 1; Asc-1; Solute carrier family 7 member 10; SLC7A10; ASC1
Antibody/Peptide Pairs
AAA1 peptide (MBS9225672) is used for blocking the activity of AAA1 antibody (MBS9211271)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
495-523
Immunogen Sequence Length
523
OMIM
607959
3D Structure
ModBase 3D Structure for Q9NS82
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human
Specificity
This AAA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495-523 amino acids from the C-terminal region of human AAA1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (lot specific)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-SLC7A10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SLC7A10 antibody
SLC7A10, in association with 4F2HC (SLC3A2; MIM 158070),
mediates high-affinity transport of D-serine and several other
neutral amino acids (Nakauchi et al., 2000 [PubMed
10863037]).
Product Categories/Family for anti-SLC7A10 antibody
Applications Tested/Suitable for anti-SLC7A10 antibody
Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)
Application Notes for anti-SLC7A10 antibody
WB~~1:1000

Western Blot (WB) of anti-SLC7A10 antibody
AAA1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the AAA1 antibody detected the AAA1 protein (arrow).
anti-SLC7A10 antibody Western Blot (WB) (WB) image
Flow Cytometry (FC/FACS) of anti-SLC7A10 antibody
AAA1 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
anti-SLC7A10 antibody Flow Cytometry (FC/FACS) (FC/FACS) image
NCBI/Uniprot data below describe general gene information for SLC7A10. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56798
NCBI Official Full Name
asc-type amino acid transporter 1
NCBI Official Synonym Full Names
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
NCBI Official Symbol
SLC7A10  [Similar Products]
NCBI Official Synonym Symbols
ASC1; asc-1; HASC-1
  [Similar Products]
NCBI Protein Information
asc-type amino acid transporter 1
UniProt Protein Name
Asc-type amino acid transporter 1
UniProt Synonym Protein Names
Solute carrier family 7 member 10
UniProt Gene Name
SLC7A10  [Similar Products]
UniProt Synonym Gene Names
ASC1; Asc-1  [Similar Products]
UniProt Entry Name
AAA1_HUMAN
NCBI Summary for SLC7A10
SLC7A10, in association with 4F2HC (SLC3A2; MIM 158070), mediates high-affinity transport of D-serine and several other neutral amino acids (Nakauchi et al., 2000 [PubMed 10863037]).[supplied by OMIM, Mar 2008]
UniProt Comments for SLC7A10
SLC7A10: Sodium-independent, high affinity transport of small neutral D- and L-amino acids. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse. Belongs to the amino acid-polyamine-organocation (APC) superfamily.

Protein type: Transporter, SLC family; Transporter; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: L-serine transmembrane transporter activity; neutral amino acid transmembrane transporter activity

Biological Process: D-alanine transport; neutral amino acid transport; amino acid transport; ion transport; blood coagulation; transmembrane transport; D-serine transport; leukocyte migration; L-serine transport
Product References and Citations for anti-SLC7A10 antibody
Imielinski, M., et al. Nat. Genet. 41(12):1335-1340(2009)
Broer, S. Physiol. Rev. 88(1):249-286(2008)
Xu, D., et al. Mol. Cell Proteomics 4(8):1061-1071(2005)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-SLC7A10 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >10 publications with SLC7A10 and Brain
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