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anti-AAAS antibody :: Rabbit anti-Human AAAS Polyclonal Antibody

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Catalog # MBS9217015
Unit / Price
  0.05 mL  /  $150 +1 FREE 8GB USB
  0.2 mL  /  $340 +1 FREE 8GB USB
Western Blot (WB)
Product Name

AAAS, Polyclonal Antibody

Also Known As

AAAS Antibody (C-Term)

Product Synonym Names
Purified Rabbit Polyclonal Antibody (Pab); Aladin; Adracalin; AAAS; ADRACALA
Antibody/Peptide Pairs
AAAS peptide (MBS9230576) is used for blocking the activity of AAAS antibody (MBS9217015)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
3D Structure
ModBase 3D Structure for Q9NRG9
Species Reactivity
Antigen Type
Synthesized Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-AAAS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AAAS antibody
Plays a role in the normal development of the peripheral and central nervous system.
Product Categories/Family for anti-AAAS antibody
Applications Tested/Suitable for anti-AAAS antibody
Western Blot (WB)
Application Notes for anti-AAAS antibody

Western Blot (WB) of anti-AAAS antibody
All lanes : Anti-AAAS Antibody (C-Term) at 1:2000 dilution
Lane 1: 293T/17 whole cell lysate
Lane 2: Hela whole cell lysate
Lysates/proteins at 20 ug per lane.
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 60 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
anti-AAAS antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for AAAS. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
55,814 Da
NCBI Official Full Name
aladin isoform 2
NCBI Official Synonym Full Names
aladin WD repeat nucleoporin
NCBI Official Symbol
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
UniProt Protein Name
UniProt Synonym Protein Names
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
ADRACALA  [Similar Products]
UniProt Entry Name
NCBI Summary for AAAS
The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
UniProt Comments for AAAS
AAAS: Plays a role in the normal development of the peripheral and central nervous system. Defects in AAAS are the cause of achalasia-addisonianism- alacrima syndrome (AAAS); also known as triple-A syndrome or Allgrove syndrome. AAAS is an autosomal recessive disorder characterized by adreno-corticotropic hormone (ACTH)- resistant adrenal failure, achalasia of the esophageal cardia and alacrima. The syndrome is associated with variable and progressive neurological impairment involving the central, peripheral, and autonomic nervous system. Other features such as palmoplantar hyperkeratosis, short stature, facial dysmorphy and osteoporosis may also be present. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Nuclear envelope

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: centrosome; cytoplasm; membrane; nuclear envelope; nuclear membrane; nuclear pore; nucleoplasm; nucleus

Biological Process: carbohydrate metabolic process; cellular protein metabolic process; cytokine and chemokine mediated signaling pathway; fertilization; gene expression; glucose transport; hexose transport; learning; mitotic cell cycle; mitotic nuclear envelope disassembly; modification by virus of host cellular process; mRNA transport; nucleocytoplasmic transport; post-translational protein modification; protein sumoylation; protein transport; regulation of nucleocytoplasmic transport; RNA-mediated gene silencing; transmembrane transport; tRNA processing; viral infectious cycle; viral reproduction; viral transcription; virus-host interaction

Disease: Achalasia-addisonianism-alacrima Syndrome
Product References and Citations for anti-AAAS antibody
Tullio-Pelet A.,et al.Nat. Genet. 26:332-335(2000). Handschug K.,et al.Hum. Mol. Genet. 10:283-290(2001). Li X.,et al.Mol. Biol. Rep. 32:127-131(2005). Li Y.,et al.Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004).

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