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anti-AANAT antibody :: Rabbit anti-Human AANAT Polyclonal Antibody

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Catalog # MBS9131825
Unit / Price
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  0.1 mL  /  $305 +1 FREE 8GB USB
  0.2 mL  /  $460 +1 FREE 8GB USB
Western Blot (WB)
Product Name

AANAT, Polyclonal Antibody

Full Product Name

AANAT Polyclonal Antibody

Product Synonym Names
DSPS; SNAT
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
U40347 mRNA
3D Structure
ModBase 3D Structure for Q16613
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity Purification
Immunogen
A synthetic peptide of human AANAT
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at 4 degree C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-AANAT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AANAT antibody
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-AANAT antibody
Applications Tested/Suitable for anti-AANAT antibody
Western Blot (WB)
Application Notes for anti-AANAT antibody
WB: 1:500 - 1:1000

Western Blot (WB) of anti-AANAT antibody
Western blot analysis of extracts of 293T cells, using AANAT antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
anti-AANAT antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for AANAT. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23kDa
NCBI Official Full Name
Serotonin N-acetyltransferase
NCBI Official Synonym Full Names
aralkylamine N-acetyltransferase
NCBI Official Symbol
AANAT  [Similar Products]
NCBI Official Synonym Symbols
DSPS; SNAT
  [Similar Products]
NCBI Protein Information
serotonin N-acetyltransferase
UniProt Protein Name
Serotonin N-acetyltransferase
UniProt Synonym Protein Names
Aralkylamine N-acetyltransferase; AA-NAT
UniProt Gene Name
AANAT  [Similar Products]
UniProt Synonym Gene Names
SNAT; Serotonin acetylase; AA-NAT  [Similar Products]
NCBI Summary for AANAT
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
UniProt Comments for AANAT
Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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