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anti-ABCA5 antibody :: Goat ABCA5 Polyclonal Antibody

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Catalog # MBS421977
Unit / Price
  0.1 mg  /  $225 +1 FREE 8GB USB
anti-ABCA5 antibody
Product Name

ABCA5, Polyclonal Antibody

Also Known As

Goat anti-ABCA5 Antibody

Product Synonym Names
ABCA5; ATP-binding cassette, sub-family A (ABC1), member 5; ABC13; DKFZp451F117; DKFZp779N2435; EST90625; FLJ16381; ATP-binding cassette A5; ATP-binding cassette, sub-family A, member 5; ABCA5 antibody; ATP-binding cassette; sub-family A (ABC1); member 5 antibody; ABC13 antibody; DKFZp451F117 antibody; DKFZp779N2435 antibody; FLJ16381 antibody; ATP-binding cassette A5 antibody; ATP-binding cassette; sub-family A; member 5 antibody
Antibody/Peptide Pairs
ABCA5 peptide (MBS426643) is used for blocking the activity of ABCA5 antibody (MBS421977)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1642
Immunogen Sequence
DYSSETSEDD DSLKC
OMIM
612503
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence DYSSETSEDDDSLKC, from the internal region of the protein sequence according to NP_758424.1.
Epitope
Internal region
Note
Reported variants represent identical protein: NP_061142.2 and NP_758424.1
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-ABCA5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ABCA5 antibody
Peptide ELISA (EIA)
Application Notes for anti-ABCA5 antibody
Peptide ELISA: Antibody detection limit dilution 1: 1000.
Western Blot: Preliminary experiments in Human Brain (Cerebellum, Cerebral Cortex) lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
NCBI/Uniprot data below describe general gene information for ABCA5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
99,273 Da
NCBI Official Full Name
ATP-binding cassette sub-family A member 5
NCBI Official Synonym Full Names
ATP binding cassette subfamily A member 5
NCBI Official Symbol
ABCA5  [Similar Products]
NCBI Official Synonym Symbols
ABC13; EST90625
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family A member 5
UniProt Protein Name
ATP-binding cassette sub-family A member 5
Protein Family
UniProt Gene Name
ABCA5  [Similar Products]
UniProt Synonym Gene Names
KIAA1888  [Similar Products]
UniProt Entry Name
ABCA5_HUMAN
NCBI Summary for ABCA5
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCA5
ABCA5: May play a role in the processing of autolysosomes. Belongs to the ABC transporter superfamily. ABCA family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, ABC family; Transporter

Chromosomal Location of Human Ortholog: 17q24.3

Cellular Component: Golgi membrane; integral to membrane; intracellular membrane-bound organelle; late endosome; late endosome membrane; lysosomal membrane; lysosome

Molecular Function: ATP binding; ATPase activity, coupled to transmembrane movement of substances

Biological Process: cholesterol efflux; lipid transport; metabolic process; reverse cholesterol transport; transmembrane transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-ABCA5 antibody
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