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anti-ABCA6 antibody :: Goat ABCA6 Polyclonal Antibody

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Catalog # MBS422042
Unit / Price
  0.1 mg  /  $225 +1 FREE 8GB USB
anti-ABCA6 antibody
Product Name

ABCA6, Polyclonal Antibody

Also Known As

Goat anti-ABCA6 Antibody

Product Synonym Names
ABCA6; ATP-binding cassette, sub-family A (ABC1), member 6; EST155051; FLJ43498; ABC transporter ABCA6; ATP-binding cassette A6; ATP-binding cassette, sub-family A, member 6; ABCA6 antibody; ATP-binding cassette; sub-family A (ABC1); member 6 antibody; EST155051 antibody; FLJ43498 antibody; ABC transporter ABCA6 antibody; ATP-binding cassette A6 antibody; ATP-binding cassette; sub-family A; member 6 antibody
Antibody/Peptide Pairs
ABCA6 peptide (MBS425603) is used for blocking the activity of ABCA6 antibody (MBS422042)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1617
Immunogen Sequence
RWKLLPHSDE P
OMIM
612504
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-RWKLLPHSDEP, from the C Terminus of the protein sequence according to NP_525023.2.
Epitope
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-ABCA6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ABCA6 antibody
Peptide ELISA (EIA)
Application Notes for anti-ABCA6 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Preliminary experiments gave an approx 50kDa band in Human Brain (Cerebellum, Cerebral Cortex, Frontal Cortex) lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 184kDa according to NP_525023.2. The 50kDa band was successfully blocked by incubation with the immunizing peptide.
NCBI/Uniprot data below describe general gene information for ABCA6. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
21,356 Da
NCBI Official Full Name
ATP-binding cassette sub-family A member 6
NCBI Official Synonym Full Names
ATP binding cassette subfamily A member 6
NCBI Official Symbol
ABCA6  [Similar Products]
NCBI Official Synonym Symbols
EST155051
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family A member 6
UniProt Protein Name
ATP-binding cassette sub-family A member 6
Protein Family
UniProt Gene Name
ABCA6  [Similar Products]
UniProt Entry Name
ABCA6_HUMAN
NCBI Summary for ABCA6
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCA6
ABCA6: Probable transporter which may play a role in macrophage lipid homeostasis. Belongs to the ABC transporter superfamily. ABCA family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, ABC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q24.3

Cellular Component: integral to membrane; intracellular membrane-bound organelle

Molecular Function: ATP binding; ATPase activity, coupled to transmembrane movement of substances

Biological Process: lipid transport; metabolic process; transmembrane transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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