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anti-ABCA8 antibody :: Goat ABCA8 Polyclonal Antibody

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Catalog # MBS422044
Unit / Price
  0.1 mg  /  $225 +1 FREE 8GB USB
anti-ABCA8 antibody
Product Name

ABCA8, Polyclonal Antibody

Also Known As

Goat anti-ABCA8 Antibody

Product Synonym Names
ABCA8; ATP-binding cassette, sub-family A (ABC1), member 8; KIAA0822; MGC163152; ATP-binding cassette, sub-family A member 8; ABCA8 antibody; ATP-binding cassette; sub-family A (ABC1); member 8 antibody; KIAA0822 antibody; MGC163152 antibody; ATP-binding cassette; sub-family A member 8 antibody
Antibody/Peptide Pairs
ABCA8 peptide (MBS425865) is used for blocking the activity of ABCA8 antibody (MBS422044)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
Immunogen Sequence
Species Reactivity
Expected from sequence similarity: Human
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
100ug specific antibody in 200ul (lot specific)
Peptide with sequence C-KEQELGDFEEDFD, from the C Terminus of the protein sequence according to NP_009099.1.
C Terminus
This antibody is expected to cross-react with the highly similar Human ABCA9, since the immunizing peptide differs from ABCA9 with only one residue (F8).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-ABCA8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ABCA8 antibody
Peptide ELISA (EIA)
Application Notes for anti-ABCA8 antibody
Peptide ELISA: Antibody detection limit dilution 1: 4000.
Western Blot: Preliminary experiments gave an approx.50-55kDa band in Human Brain (Cerebellum, Cerebral Cortex, Frontal Cortex), Heart, Skeletal Muscle and Testis lysates after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 179kDa according to NP_009099.1. The 50-55kDa band was successfully blocked by incubation with the immunizing peptide.
NCBI/Uniprot data below describe general gene information for ABCA8. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
183,677 Da
NCBI Official Full Name
ATP-binding cassette sub-family A member 8 isoform 2
NCBI Official Synonym Full Names
ATP binding cassette subfamily A member 8
NCBI Official Symbol
ABCA8  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family A member 8
UniProt Protein Name
ATP-binding cassette sub-family A member 8
Protein Family
UniProt Gene Name
ABCA8  [Similar Products]
UniProt Synonym Gene Names
KIAA0822  [Similar Products]
UniProt Entry Name
NCBI Summary for ABCA8
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
UniProt Comments for ABCA8
ABCA8: ATP-dependent lipophilic drug transporter. Belongs to the ABC transporter superfamily. ABCA family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transporter, ABC family; Hydrolase; Transporter

Chromosomal Location of Human Ortholog: 17q24

Cellular Component: integral to membrane; mitochondrial inner membrane; plasma membrane

Molecular Function: ATP binding; ATPase activity, coupled to transmembrane movement of substances; xenobiotic-transporting ATPase activity

Biological Process: lipid transport; metabolic process; multidrug transport; transmembrane transport; transport; xenobiotic transport
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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