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anti-ABCB10 antibody :: Rabbit anti-Human ABCB10 Polyclonal Antibody

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Catalog # MBS9214924
Unit / Price
  0.08 mL  /  $150 +1 FREE 8GB USB
  0.4 mL  /  $340 +1 FREE 8GB USB
Product Name

ABCB10, Polyclonal Antibody

Also Known As

ABCB10 Antibody (N-term)

Product Synonym Names
ATP-binding cassette sub-family B member 10; mitochondrial; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10
Antibody/Peptide Pairs
ABCB10 peptide (MBS9225891) is used for blocking the activity of ABCB10 antibody (MBS9214924)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
1-27
Immunogen Sequence Length
738
OMIM
605454
3D Structure
ModBase 3D Structure for Q9NRK6
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human
Specificity
This ABCB10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-27 amino acids from the N-terminal region of human ABCB10.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.25 (lot specific)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ABCB10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABCB10 antibody
The membrane-associated protein ABCB10 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown.
Applications Tested/Suitable for anti-ABCB10 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-ABCB10 antibody
WB~~1:1000

Western Blot (WB) of anti-ABCB10 antibody
All lanes : Anti-ABCB10 Antibody (S16) at 1:1000-1:2000 dilution
Lane 1: K562 whole cell lysates
Lane 2: Raji whole cell lysates

Lysates/proteins at 20 ug per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution

Predicted band size : 79 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.
anti-ABCB10 antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-ABCB10 antibody
ABCB10 Antibody (S16) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the ABCB10 antibody detected the ABCB10 protein (arrow).
anti-ABCB10 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ABCB10 antibody
ABCB10 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABCB10 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-ABCB10 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ABCB10. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
79148
NCBI Official Full Name
ATP-binding cassette sub-family B member 10, mitochondrial
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family B (MDR/TAP), member 10
NCBI Official Symbol
ABCB10  [Similar Products]
NCBI Official Synonym Symbols
M-ABC2; MTABC2; EST20237
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family B member 10, mitochondrial
UniProt Protein Name
ATP-binding cassette sub-family B member 10, mitochondrial
UniProt Synonym Protein Names
ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2
Protein Family
UniProt Gene Name
ABCB10  [Similar Products]
UniProt Synonym Gene Names
ABC transporter 10 protein; M-ABC2  [Similar Products]
UniProt Entry Name
ABCBA_HUMAN
NCBI Summary for ABCB10
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCB10
ABCB10: May mediate critical mitochondrial transport functions related to heme biosynthesis. Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.

Protein type: Transporter; Membrane protein, integral; Hydrolase; Membrane protein, multi-pass; Transporter, ABC family; Mitochondrial

Chromosomal Location of Human Ortholog: 1q42.13

Cellular Component: mitochondrial inner membrane

Molecular Function: protein homodimerization activity; ATPase activity, coupled to transmembrane movement of substances; transporter activity; ATP binding

Biological Process: transport; metabolic process; transmembrane transport
Product References and Citations for anti-ABCB10 antibody
Zhang, F., et al., J. Biol. Chem. 275(30):23287-23294 (2000). Allikmets, R., et al., Mamm. Genome 6(2):114-117 (1995). Zhang, F., et al., FEBS Lett. 478 (1-2), 89-94 (2000).

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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